| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50128096 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_46981 (CHEMBL659748) |
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| Ki | 69±n/a nM |
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| Citation |  Wrobleski, ST; Chen, P; Hynes, J; Lin, S; Norris, DJ; Pandit, CR; Spergel, S; Wu, H; Tokarski, JS; Chen, X; Gillooly, KM; Kiener, PA; McIntyre, KW; Patil-Koota, V; Shuster, DJ; Turk, LA; Yang, G; Leftheris, K Rational design and synthesis of an orally active indolopyridone as a novel conformationally constrained cannabinoid ligand possessing antiinflammatory properties. J Med Chem46:2110-6 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM50128096 |
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| n/a |
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| Name | BDBM50128096 |
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| Synonyms: | 7-Methoxy-1-(2-morpholin-4-yl-ethyl)-1H-indazole-3-carboxylic acid (2-chloro-6-fluoro-benzyl)-isopropyl-amide | CHEMBL67006 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H30ClFN4O3 |
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| Mol. Mass. | 488.982 |
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| SMILES | COc1cccc2c(nn(CCN3CCOCC3)c12)C(=O)N(Cc1c(F)cccc1Cl)C(C)C |
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| Structure | 
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