| Reaction Details |
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 | Report a problem with these data |
| Target | Translocator protein |
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| Ligand | BDBM50131734 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_37039 (CHEMBL650835) |
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| IC50 | 32±n/a nM |
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| Citation |  Cappelli, A; Pericot Mohr, G; Gallelli, A; Giuliani, G; Anzini, M; Vomero, S; Fresta, M; Porcu, P; Maciocco, E; Concas, A; Biggio, G; Donati, A Structure-activity relationships in carboxamide derivatives based on the targeted delivery of radionuclides and boron atoms by means of peripheral benzodiazepine receptor ligands. J Med Chem46:3568-71 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Translocator protein |
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| Name: | Translocator protein |
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| Synonyms: | Benzodiazepine receptors; peripheral & central | Bzrp | Mbr | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR) | Peripheral-Type Benzodiazepine Receptor | TSPO_RAT | Tspo |
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| Type: | Mitochondrion membrane protein |
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| Mol. Mass.: | 18945.84 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Competitive binding experiments were performed on rat kidney mitochondrial membranes. |
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| Residue: | 169 |
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| Sequence: | MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAM
GYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVAT
ATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
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| BDBM50131734 |
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| n/a |
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| Name | BDBM50131734 |
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| Synonyms: | 3-Methyl-4-phenyl-quinoline-2-carboxylic acid methyl-prop-2-ynyl-amide | CHEMBL119787 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H18N2O |
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| Mol. Mass. | 314.3804 |
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| SMILES | CN(CC#C)C(=O)c1nc2ccccc2c(-c2ccccc2)c1C |
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| Structure | 
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