Compile Data Set for Download or QSAR

Found 17 hits with Last Name = 'fresta' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Translocator protein (Rattus norvegicus (rat))	BDBM50131724 (3-Chloromethyl-4-phenyl-quinoline-2-carboxylic aci...) Show SMILES CN(Cc1ccccc1)C(=O)c1nc2ccccc2c(-c2ccccc2)c1CCl Show InChI InChI=1S/C25H21ClN2O/c1-28(17-18-10-4-2-5-11-18)25(29)24-21(16-26)23(19-12-6-3-7-13-19)20-14-8-9-15-22(20)27-24/h2-15H,16-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.450	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibitory activity against specific binding of [3H]-CB 34 to peripheral benzodiazepine receptor in rat cortical membranes was evaluated				J Med Chem 46: 3568-71 (2003) Article DOI: 10.1021/jm034068b BindingDB Entry DOI: 10.7270/Q2D79C5Z
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50131729 (4-(2-Fluoro-phenyl)-3-methyl-quinoline-2-carboxyli...) Show SMILES CN(Cc1ccccc1)C(=O)c1nc2ccccc2c(c1C)-c1ccccc1F |(11.02,-3.02,;11.02,-1.48,;12.35,-.71,;13.68,-1.47,;15,-.68,;16.34,-1.45,;16.36,-2.99,;15.03,-3.76,;13.68,-3.01,;9.68,-.72,;9.67,.82,;8.35,-1.5,;7.01,-.73,;5.69,-1.52,;4.35,-.75,;3.02,-1.52,;3.02,-3.06,;4.35,-3.83,;5.69,-3.06,;7.03,-3.83,;8.36,-3.04,;9.69,-3.81,;7.03,-5.35,;5.69,-6.12,;5.69,-7.66,;7.03,-8.43,;8.36,-7.65,;8.36,-6.12,;9.69,-5.34,)| Show InChI InChI=1S/C25H21FN2O/c1-17-23(19-12-6-8-14-21(19)26)20-13-7-9-15-22(20)27-24(17)25(29)28(2)16-18-10-4-3-5-11-18/h3-15H,16H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibitory activity against specific binding of [3H]-CB 34 to peripheral benzodiazepine receptor in rat cortical membranes was evaluated				J Med Chem 46: 3568-71 (2003) Article DOI: 10.1021/jm034068b BindingDB Entry DOI: 10.7270/Q2D79C5Z
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50059749 (3-Methyl-4-phenyl-quinoline-2-carboxylic acid benz...) Show SMILES CN(Cc1ccccc1)C(=O)c1nc2ccccc2c(c1C)-c1ccccc1 Show InChI InChI=1S/C25H22N2O/c1-18-23(20-13-7-4-8-14-20)21-15-9-10-16-22(21)26-24(18)25(28)27(2)17-19-11-5-3-6-12-19/h3-16H,17H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibitory activity against specific binding of [3H]-CB 34 to peripheral benzodiazepine receptor in rat cortical membranes was evaluated				J Med Chem 46: 3568-71 (2003) Article DOI: 10.1021/jm034068b BindingDB Entry DOI: 10.7270/Q2D79C5Z
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM22032 (1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoq...) Show SMILES CCC(C)N(C)C(=O)c1cc2ccccc2c(n1)-c1ccccc1Cl Show InChI InChI=1S/C21H21ClN2O/c1-4-14(2)24(3)21(25)19-13-15-9-5-6-10-16(15)20(23-19)17-11-7-8-12-18(17)22/h5-14H,4H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibitory activity against specific binding of [3H]-CB 34 to peripheral benzodiazepine receptor in rat cortical membranes was evaluated				J Med Chem 46: 3568-71 (2003) Article DOI: 10.1021/jm034068b BindingDB Entry DOI: 10.7270/Q2D79C5Z
					More data for this Ligand-Target Pair				3D Structure (crystal)
Translocator protein (Rattus norvegicus (rat))	BDBM50131721 (3-Hydroxymethyl-4-phenyl-quinoline-2-carboxylic ac...) Show SMILES CN(Cc1ccccc1)C(=O)c1nc2ccccc2c(-c2ccccc2)c1CO Show InChI InChI=1S/C25H22N2O2/c1-27(16-18-10-4-2-5-11-18)25(29)24-21(17-28)23(19-12-6-3-7-13-19)20-14-8-9-15-22(20)26-24/h2-15,28H,16-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibitory activity against specific binding of [3H]-CB 34 to peripheral benzodiazepine receptor in rat cortical membranes was evaluated				J Med Chem 46: 3568-71 (2003) Article DOI: 10.1021/jm034068b BindingDB Entry DOI: 10.7270/Q2D79C5Z
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50131727 (3-Methyl-4-phenyl-naphthalene-2-carboxylic acid be...) Show SMILES CN(Cc1ccccc1)C(=O)c1cc2ccccc2c(c1C)-c1ccccc1 Show InChI InChI=1S/C26H23NO/c1-19-24(26(28)27(2)18-20-11-5-3-6-12-20)17-22-15-9-10-16-23(22)25(19)21-13-7-4-8-14-21/h3-17H,18H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibitory activity against specific binding of [3H]-CB 34 to peripheral benzodiazepine receptor in rat cortical membranes was evaluated				J Med Chem 46: 3568-71 (2003) Article DOI: 10.1021/jm034068b BindingDB Entry DOI: 10.7270/Q2D79C5Z
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50131730 (3-Methyl-4-phenyl-quinoline-2-carboxylic acid dibe...) Show SMILES Cc1c(nc2ccccc2c1-c1ccccc1)C(=O)N(Cc1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C31H26N2O/c1-23-29(26-17-9-4-10-18-26)27-19-11-12-20-28(27)32-30(23)31(34)33(21-24-13-5-2-6-14-24)22-25-15-7-3-8-16-25/h2-20H,21-22H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibitory activity against specific binding of [3H]-CB 34 to peripheral benzodiazepine receptor in rat cortical membranes was evaluated				J Med Chem 46: 3568-71 (2003) Article DOI: 10.1021/jm034068b BindingDB Entry DOI: 10.7270/Q2D79C5Z
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50131726 (3-Diethylaminomethyl-4-phenyl-quinoline-2-carboxyl...) Show SMILES CCN(CC)Cc1c(nc2ccccc2c1-c1ccccc1)C(=O)N(C)Cc1ccccc1 Show InChI InChI=1S/C29H31N3O/c1-4-32(5-2)21-25-27(23-16-10-7-11-17-23)24-18-12-13-19-26(24)30-28(25)29(33)31(3)20-22-14-8-6-9-15-22/h6-19H,4-5,20-21H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibitory activity against specific binding of [3H]-CB 34 to peripheral benzodiazepine receptor in rat cortical membranes was evaluated				J Med Chem 46: 3568-71 (2003) Article DOI: 10.1021/jm034068b BindingDB Entry DOI: 10.7270/Q2D79C5Z
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50131728 (3-[(Benzyl-ethyl-amino)-methyl]-4-phenyl-quinoline...) Show SMILES CCN(Cc1ccccc1)Cc1c(nc2ccccc2c1-c1ccccc1)C(=O)N(C)Cc1ccccc1 Show InChI InChI=1S/C34H33N3O/c1-3-37(24-27-17-9-5-10-18-27)25-30-32(28-19-11-6-12-20-28)29-21-13-14-22-31(29)35-33(30)34(38)36(2)23-26-15-7-4-8-16-26/h4-22H,3,23-25H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibitory activity against specific binding of [3H]-CB 34 to peripheral benzodiazepine receptor in rat cortical membranes was evaluated				J Med Chem 46: 3568-71 (2003) Article DOI: 10.1021/jm034068b BindingDB Entry DOI: 10.7270/Q2D79C5Z
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50131734 (3-Methyl-4-phenyl-quinoline-2-carboxylic acid meth...) Show SMILES CN(CC#C)C(=O)c1nc2ccccc2c(-c2ccccc2)c1C Show InChI InChI=1S/C21H18N2O/c1-4-14-23(3)21(24)20-15(2)19(16-10-6-5-7-11-16)17-12-8-9-13-18(17)22-20/h1,5-13H,14H2,2-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibitory activity against specific binding of [3H]-CB 34 to peripheral benzodiazepine receptor in rat cortical membranes was evaluated				J Med Chem 46: 3568-71 (2003) Article DOI: 10.1021/jm034068b BindingDB Entry DOI: 10.7270/Q2D79C5Z
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50131733 (4-Phenyl-quinoline-2-carboxylic acid benzyl-methyl...) Show SMILES CN(Cc1ccccc1)C(=O)c1cc(-c2ccccc2)c2ccccc2n1 Show InChI InChI=1S/C24H20N2O/c1-26(17-18-10-4-2-5-11-18)24(27)23-16-21(19-12-6-3-7-13-19)20-14-8-9-15-22(20)25-23/h2-16H,17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibitory activity against specific binding of [3H]-CB 34 to peripheral benzodiazepine receptor in rat cortical membranes was evaluated				J Med Chem 46: 3568-71 (2003) Article DOI: 10.1021/jm034068b BindingDB Entry DOI: 10.7270/Q2D79C5Z
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50131731 (4-Phenyl-naphthalene-2-carboxylic acid benzyl-meth...) Show SMILES CN(Cc1ccccc1)C(=O)c1cc(-c2ccccc2)c2ccccc2c1 Show InChI InChI=1S/C25H21NO/c1-26(18-19-10-4-2-5-11-19)25(27)22-16-21-14-8-9-15-23(21)24(17-22)20-12-6-3-7-13-20/h2-17H,18H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibitory activity against specific binding of [3H]-CB 34 to peripheral benzodiazepine receptor in rat cortical membranes was evaluated				J Med Chem 46: 3568-71 (2003) Article DOI: 10.1021/jm034068b BindingDB Entry DOI: 10.7270/Q2D79C5Z
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50131722 (4-(2-Fluoro-phenyl)-3-methyl-quinoline-2-carboxyli...) Show SMILES Cc1c(nc2ccccc2c1-c1ccccc1F)C(=O)NCc1ccccc1 |(9.69,-3.81,;8.36,-3.04,;8.35,-1.5,;7.01,-.73,;5.69,-1.52,;4.35,-.75,;3.02,-1.52,;3.02,-3.06,;4.35,-3.83,;5.69,-3.06,;7.03,-3.83,;7.03,-5.35,;5.69,-6.12,;5.69,-7.66,;7.03,-8.43,;8.36,-7.65,;8.36,-6.12,;9.69,-5.34,;9.68,-.72,;9.67,.82,;11.02,-1.48,;12.35,-.71,;13.68,-1.47,;15,-.68,;16.34,-1.45,;16.36,-2.99,;15.03,-3.76,;13.68,-3.01,)| Show InChI InChI=1S/C24H19FN2O/c1-16-22(18-11-5-7-13-20(18)25)19-12-6-8-14-21(19)27-23(16)24(28)26-15-17-9-3-2-4-10-17/h2-14H,15H2,1H3,(H,26,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibitory activity against specific binding of [3H]-CB 34 to peripheral benzodiazepine receptor in rat cortical membranes was evaluated				J Med Chem 46: 3568-71 (2003) Article DOI: 10.1021/jm034068b BindingDB Entry DOI: 10.7270/Q2D79C5Z
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50131732 (4-Phenyl-naphthalene-2-carboxylic acid benzylamide...) Show SMILES O=C(NCc1ccccc1)c1cc(-c2ccccc2)c2ccccc2c1 Show InChI InChI=1S/C24H19NO/c26-24(25-17-18-9-3-1-4-10-18)21-15-20-13-7-8-14-22(20)23(16-21)19-11-5-2-6-12-19/h1-16H,17H2,(H,25,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibitory activity against specific binding of [3H]-CB 34 to peripheral benzodiazepine receptor in rat cortical membranes was evaluated				J Med Chem 46: 3568-71 (2003) Article DOI: 10.1021/jm034068b BindingDB Entry DOI: 10.7270/Q2D79C5Z
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50131723 (3-Methyl-4-phenyl-naphthalene-2-carboxylic acid be...) Show SMILES Cc1c(cc2ccccc2c1-c1ccccc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C25H21NO/c1-18-23(25(27)26-17-19-10-4-2-5-11-19)16-21-14-8-9-15-22(21)24(18)20-12-6-3-7-13-20/h2-16H,17H2,1H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibitory activity against specific binding of [3H]-CB 34 to peripheral benzodiazepine receptor in rat cortical membranes was evaluated				J Med Chem 46: 3568-71 (2003) Article DOI: 10.1021/jm034068b BindingDB Entry DOI: 10.7270/Q2D79C5Z
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50059735 (3-Methyl-4-phenyl-quinoline-2-carboxylic acid benz...) Show SMILES Cc1c(nc2ccccc2c1-c1ccccc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C24H20N2O/c1-17-22(19-12-6-3-7-13-19)20-14-8-9-15-21(20)26-23(17)24(27)25-16-18-10-4-2-5-11-18/h2-15H,16H2,1H3,(H,25,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibitory activity against specific binding of [3H]-CB 34 to peripheral benzodiazepine receptor in rat cortical membranes was evaluated				J Med Chem 46: 3568-71 (2003) Article DOI: 10.1021/jm034068b BindingDB Entry DOI: 10.7270/Q2D79C5Z
					More data for this Ligand-Target Pair
Translocator protein (Rattus norvegicus (rat))	BDBM50131725 (4-Phenyl-quinoline-2-carboxylic acid benzylamide |...) Show SMILES O=C(NCc1ccccc1)c1cc(-c2ccccc2)c2ccccc2n1 Show InChI InChI=1S/C23H18N2O/c26-23(24-16-17-9-3-1-4-10-17)22-15-20(18-11-5-2-6-12-18)19-13-7-8-14-21(19)25-22/h1-15H,16H2,(H,24,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibitory activity against specific binding of [3H]-CB 34 to peripheral benzodiazepine receptor in rat cortical membranes was evaluated				J Med Chem 46: 3568-71 (2003) Article DOI: 10.1021/jm034068b BindingDB Entry DOI: 10.7270/Q2D79C5Z
					More data for this Ligand-Target Pair