| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neutrophil collagenase |
|---|
| Ligand | BDBM50146816 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_105208 (CHEMBL713847) |
|---|
| IC50 | >100000±n/a nM |
|---|
| Citation |  Breuer, E; Salomon, CJ; Katz, Y; Chen, W; Lu, S; Röschenthaler, GV; Hadar, R; Reich, R Carbamoylphosphonates, a new class of in vivo active matrix metalloproteinase inhibitors. 1. Alkyl- and cycloalkylcarbamoylphosphonic acids. J Med Chem47:2826-32 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neutrophil collagenase |
|---|
| Name: | Neutrophil collagenase |
|---|
| Synonyms: | CLG1 | MMP-8 | MMP8 | MMP8_HUMAN | Matrix metalloproteinase-8 | Neutrophil collagenase precursor | PMNL collagenase | PMNL-CL |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 53413.48 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P22894 |
|---|
| Residue: | 467 |
|---|
| Sequence: | MFSLKTLPFLLLLHVQISKAFPVSSKEKNTKTVQDYLEKFYQLPSNQYQSTRKNGTNVIV
EKLKEMQRFFGLNVTGKPNEETLDMMKKPRCGVPDSGGFMLTPGNPKWERTNLTYRIRNY
TPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPNGIL
AHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYA
FRETSNYSLPQDDIDGIQAIYGLSSNPIQPTGPSTPKPCDPSLTFDAITTLRGEILFFKD
RYFWRRHPQLQRVEMNFISLFWPSLPTGIQAAYEDFDRDLIFLFKGNQYWALSGYDILQG
YPKDISNYGFPSSVQAIDAAVFYRSKTYFFVNDQFWRYDNQRQFMEPGYPKSISGAFPGI
ESKVDAVFQQEHFFHVFSGPRYYAFDLIAQRVTRVARGNKWLNCRYG
|
|
|
|---|
| BDBM50146816 |
|---|
| n/a |
|---|
| Name | BDBM50146816 |
|---|
| Synonyms: | (cyclopentylamino)carbonylphosphonic acid | CHEMBL316997 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C6H12NO4P |
|---|
| Mol. Mass. | 193.1375 |
|---|
| SMILES | OP(O)(=O)C(=O)NC1CCCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
