Found 225 hits with Last Name = 'breuer' and Initial = 'e' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50146809
((methylamino)carbonylphosphonic acid | CHEMBL97388)Show InChI InChI=1S/C2H6NO4P/c1-3-2(4)8(5,6)7/h1H3,(H,3,4)(H2,5,6,7) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-2 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50146800
((cyclobutylamino)carbonylphosphonic acid | CHEMBL9...)Show InChI InChI=1S/C5H10NO4P/c7-5(11(8,9)10)6-4-2-1-3-4/h4H,1-3H2,(H,6,7)(H2,8,9,10) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-8 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50146816
((cyclopentylamino)carbonylphosphonic acid | CHEMBL...)Show InChI InChI=1S/C6H12NO4P/c8-6(12(9,10)11)7-5-3-1-2-4-5/h5H,1-4H2,(H,7,8)(H2,9,10,11) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50146816
((cyclopentylamino)carbonylphosphonic acid | CHEMBL...)Show InChI InChI=1S/C6H12NO4P/c8-6(12(9,10)11)7-5-3-1-2-4-5/h5H,1-4H2,(H,7,8)(H2,9,10,11) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-2 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50396791
(CHEMBL2172744)Show SMILES OP(O)(=O)C(=O)NCCCCCCNS(=O)(=O)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C19H25N2O7PS/c22-19(29(23,24)25)20-14-6-1-2-7-15-21-30(26,27)18-12-10-17(11-13-18)28-16-8-4-3-5-9-16/h3-5,8-13,21H,1-2,6-7,14-15H2,(H,20,22)(H2,23,24,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of human Carbonic anhydrase 2-mediated CO2 hydration by stopped-flow method |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50396793
(CHEMBL2170079)Show SMILES OP(O)(=O)C(=O)NCCCCNS(=O)(=O)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C17H21N2O7PS/c20-17(27(21,22)23)18-12-4-5-13-19-28(24,25)16-10-8-15(9-11-16)26-14-6-2-1-3-7-14/h1-3,6-11,19H,4-5,12-13H2,(H,18,20)(H2,21,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of human Carbonic anhydrase 2-mediated CO2 hydration by stopped-flow method |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50146801
((cyclohexylamino)carbonylphosphonic acid | CHEMBL3...)Show InChI InChI=1S/C7H14NO4P/c9-7(13(10,11)12)8-6-4-2-1-3-5-6/h6H,1-5H2,(H,8,9)(H2,10,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-1 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50146800
((cyclobutylamino)carbonylphosphonic acid | CHEMBL9...)Show InChI InChI=1S/C5H10NO4P/c7-5(11(8,9)10)6-4-2-1-3-4/h4H,1-3H2,(H,6,7)(H2,8,9,10) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-2 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50146815
((cyclopropylamino)carbonylphosphonic acid | CHEMBL...)Show InChI InChI=1S/C4H8NO4P/c6-4(10(7,8)9)5-3-1-2-3/h3H,1-2H2,(H,5,6)(H2,7,8,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-8 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50146805
(CHEMBL97951 | [(cyclohexylmethyl)amino]carbonylpho...)Show InChI InChI=1S/C8H16NO4P/c10-8(14(11,12)13)9-6-7-4-2-1-3-5-7/h7H,1-6H2,(H,9,10)(H2,11,12,13) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-2 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50146805
(CHEMBL97951 | [(cyclohexylmethyl)amino]carbonylpho...)Show InChI InChI=1S/C8H16NO4P/c10-8(14(11,12)13)9-6-7-4-2-1-3-5-7/h7H,1-6H2,(H,9,10)(H2,11,12,13) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50396802
(CHEMBL2172747)Show InChI InChI=1S/C9H18NO4P/c1-7(8-5-3-2-4-6-8)10-9(11)15(12,13)14/h7-8H,2-6H2,1H3,(H,10,11)(H2,12,13,14)/t7-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50146797
((propylamino)carbonylphosphonic acid | CHEMBL94346)Show InChI InChI=1S/C4H10NO4P/c1-2-3-5-4(6)10(7,8)9/h2-3H2,1H3,(H,5,6)(H2,7,8,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-2 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50396792
(CHEMBL2170080)Show SMILES OP(O)(=O)C(=O)NCCCCCNS(=O)(=O)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C18H23N2O7PS/c21-18(28(22,23)24)19-13-5-2-6-14-20-29(25,26)17-11-9-16(10-12-17)27-15-7-3-1-4-8-15/h1,3-4,7-12,20H,2,5-6,13-14H2,(H,19,21)(H2,22,23,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of human Carbonic anhydrase 2-mediated CO2 hydration by stopped-flow method |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50396791
(CHEMBL2172744)Show SMILES OP(O)(=O)C(=O)NCCCCCCNS(=O)(=O)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C19H25N2O7PS/c22-19(29(23,24)25)20-14-6-1-2-7-15-21-30(26,27)18-12-10-17(11-13-18)28-16-8-4-3-5-9-16/h3-5,8-13,21H,1-2,6-7,14-15H2,(H,20,22)(H2,23,24,25) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of human Carbonic anhydrase 1-mediated CO2 hydration by stopped-flow method |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50146802
(CHEMBL95068 | piperidin-1-ylcarbonylphosphonic aci...)Show InChI InChI=1S/C6H12NO4P/c8-6(12(9,10)11)7-4-2-1-3-5-7/h1-5H2,(H2,9,10,11) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-9 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50146815
((cyclopropylamino)carbonylphosphonic acid | CHEMBL...)Show InChI InChI=1S/C4H8NO4P/c6-4(10(7,8)9)5-3-1-2-3/h3H,1-2H2,(H,5,6)(H2,7,8,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-2 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50146816
((cyclopentylamino)carbonylphosphonic acid | CHEMBL...)Show InChI InChI=1S/C6H12NO4P/c8-6(12(9,10)11)7-5-3-1-2-4-5/h5H,1-4H2,(H,7,8)(H2,9,10,11) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-1 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50396792
(CHEMBL2170080)Show SMILES OP(O)(=O)C(=O)NCCCCCNS(=O)(=O)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C18H23N2O7PS/c21-18(28(22,23)24)19-13-5-2-6-14-20-29(25,26)17-11-9-16(10-12-17)27-15-7-3-1-4-8-15/h1,3-4,7-12,20H,2,5-6,13-14H2,(H,19,21)(H2,22,23,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of human Carbonic anhydrase 1-mediated CO2 hydration by stopped-flow method |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50396794
(CHEMBL2170078)Show SMILES OP(O)(=O)C(=O)NCCCNS(=O)(=O)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C16H19N2O7PS/c19-16(26(20,21)22)17-11-4-12-18-27(23,24)15-9-7-14(8-10-15)25-13-5-2-1-3-6-13/h1-3,5-10,18H,4,11-12H2,(H,17,19)(H2,20,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 580 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of human Carbonic anhydrase 2-mediated CO2 hydration by stopped-flow method |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50396790
(CHEMBL2172745)Show InChI InChI=1S/C16H17N2O6P/c19-15(17-10-11-18-16(20)25(21,22)23)12-6-8-14(9-7-12)24-13-4-2-1-3-5-13/h1-9H,10-11H2,(H,17,19)(H,18,20)(H2,21,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 610 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of human Carbonic anhydrase 2-mediated CO2 hydration by stopped-flow method |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50396790
(CHEMBL2172745)Show InChI InChI=1S/C16H17N2O6P/c19-15(17-10-11-18-16(20)25(21,22)23)12-6-8-14(9-7-12)24-13-4-2-1-3-5-13/h1-9H,10-11H2,(H,17,19)(H,18,20)(H2,21,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of human Carbonic anhydrase 1-mediated CO2 hydration by stopped-flow method |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50396794
(CHEMBL2170078)Show SMILES OP(O)(=O)C(=O)NCCCNS(=O)(=O)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C16H19N2O7PS/c19-16(26(20,21)22)17-11-4-12-18-27(23,24)15-9-7-14(8-10-15)25-13-5-2-1-3-6-13/h1-3,5-10,18H,4,11-12H2,(H,17,19)(H2,20,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of human Carbonic anhydrase 1-mediated CO2 hydration by stopped-flow method |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50396793
(CHEMBL2170079)Show SMILES OP(O)(=O)C(=O)NCCCCNS(=O)(=O)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C17H21N2O7PS/c20-17(27(21,22)23)18-12-4-5-13-19-28(24,25)16-10-8-15(9-11-16)26-14-6-2-1-3-7-14/h1-3,6-11,19H,4-5,12-13H2,(H,18,20)(H2,21,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of human Carbonic anhydrase 1-mediated CO2 hydration by stopped-flow method |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50396795
(CHEMBL2170077)Show SMILES OP(O)(=O)C(=O)NCCNS(=O)(=O)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C15H17N2O7PS/c18-15(25(19,20)21)16-10-11-17-26(22,23)14-8-6-13(7-9-14)24-12-4-2-1-3-5-12/h1-9,17H,10-11H2,(H,16,18)(H2,19,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 820 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of human Carbonic anhydrase 2-mediated CO2 hydration by stopped-flow method |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50396795
(CHEMBL2170077)Show SMILES OP(O)(=O)C(=O)NCCNS(=O)(=O)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C15H17N2O7PS/c18-15(25(19,20)21)16-10-11-17-26(22,23)14-8-6-13(7-9-14)24-12-4-2-1-3-5-12/h1-9,17H,10-11H2,(H,16,18)(H2,19,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 980 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of human Carbonic anhydrase 1-mediated CO2 hydration by stopped-flow method |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50146802
(CHEMBL95068 | piperidin-1-ylcarbonylphosphonic aci...)Show InChI InChI=1S/C6H12NO4P/c8-6(12(9,10)11)7-4-2-1-3-5-7/h1-5H2,(H2,9,10,11) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-2 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50146799
((isopropylamino)carbonylphosphonic acid | CHEMBL97...)Show InChI InChI=1S/C4H10NO4P/c1-3(2)5-4(6)10(7,8)9/h3H,1-2H3,(H,5,6)(H2,7,8,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50146798
((cyclooctylamino)carbonylphosphonic acid | CHEMBL9...)Show InChI InChI=1S/C9H18NO4P/c11-9(15(12,13)14)10-8-6-4-2-1-3-5-7-8/h8H,1-7H2,(H,10,11)(H2,12,13,14) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50396803
(CHEMBL2172746)Show InChI InChI=1S/C9H18NO4P/c1-7(8-5-3-2-4-6-8)10-9(11)15(12,13)14/h7-8H,2-6H2,1H3,(H,10,11)(H2,12,13,14)/t7-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50146798
((cyclooctylamino)carbonylphosphonic acid | CHEMBL9...)Show InChI InChI=1S/C9H18NO4P/c11-9(15(12,13)14)10-8-6-4-2-1-3-5-7-8/h8H,1-7H2,(H,10,11)(H2,12,13,14) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-2 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50146803
(CHEMBL97838 | morpholin-4-ylcarbonylphosphonic aci...)Show InChI InChI=1S/C5H10NO5P/c7-5(12(8,9)10)6-1-3-11-4-2-6/h1-4H2,(H2,8,9,10) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-3 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50146799
((isopropylamino)carbonylphosphonic acid | CHEMBL97...)Show InChI InChI=1S/C4H10NO4P/c1-3(2)5-4(6)10(7,8)9/h3H,1-2H3,(H,5,6)(H2,7,8,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-2 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50146813
((diethylamino)carbonylphosphonic acid | CHEMBL9705...)Show InChI InChI=1S/C5H12NO4P/c1-3-6(4-2)5(7)11(8,9)10/h3-4H2,1-2H3,(H2,8,9,10) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-2 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50146805
(CHEMBL97951 | [(cyclohexylmethyl)amino]carbonylpho...)Show InChI InChI=1S/C8H16NO4P/c10-8(14(11,12)13)9-6-7-4-2-1-3-5-7/h7H,1-6H2,(H,9,10)(H2,11,12,13) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-3 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50146806
(cyclohexanaminium hydrogen (isobutylamino)carbonyl...)Show InChI InChI=1S/C5H12NO4P/c1-4(2)3-6-5(7)11(8,9)10/h4H,3H2,1-2H3,(H,6,7)(H2,8,9,10) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-8 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50146805
(CHEMBL97951 | [(cyclohexylmethyl)amino]carbonylpho...)Show InChI InChI=1S/C8H16NO4P/c10-8(14(11,12)13)9-6-7-4-2-1-3-5-7/h7H,1-6H2,(H,9,10)(H2,11,12,13) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-9 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50396796
(CHEMBL2172751)Show InChI InChI=1S/C7H15N2O4P/c8-5-3-1-2-4-6(5)9-7(10)14(11,12)13/h5-6H,1-4,8H2,(H,9,10)(H2,11,12,13)/t5-,6+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of human Carbonic anhydrase 2-mediated CO2 hydration by stopped-flow method |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
Interstitial collagenase
(Homo sapiens (Human)) | BDBM50370325
(CHEMBL1627009)Show InChI InChI=1S/C9H18NO4P/c1-2-14-15(12,13)9(11)10-8-6-4-3-5-7-8/h8H,2-7H2,1H3,(H,10,11)(H,12,13)/p-1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-1 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50396796
(CHEMBL2172751)Show InChI InChI=1S/C7H15N2O4P/c8-5-3-1-2-4-6(5)9-7(10)14(11,12)13/h5-6H,1-4,8H2,(H,9,10)(H2,11,12,13)/t5-,6+/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of human Carbonic anhydrase 1-mediated CO2 hydration by stopped-flow method |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50146814
(CHEMBL97389 | sodium hydrogen (butylamino)carbonyl...)Show InChI InChI=1S/C5H12NO4P/c1-2-3-4-6-5(7)11(8,9)10/h2-4H2,1H3,(H,6,7)(H2,8,9,10)/p-1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-2 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50146799
((isopropylamino)carbonylphosphonic acid | CHEMBL97...)Show InChI InChI=1S/C4H10NO4P/c1-3(2)5-4(6)10(7,8)9/h3H,1-2H3,(H,5,6)(H2,7,8,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-9 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50396800
(CHEMBL2172749)Show InChI InChI=1S/C14H30N2O8P2/c1-5-21-25(19,22-6-2)13(17)15-11-9-10-12-16-14(18)26(20,23-7-3)24-8-4/h5-12H2,1-4H3,(H,15,17)(H,16,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of human Carbonic anhydrase 12-mediated CO2 hydration by stopped-flow method |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50146801
((cyclohexylamino)carbonylphosphonic acid | CHEMBL3...)Show InChI InChI=1S/C7H14NO4P/c9-7(13(10,11)12)8-6-4-2-1-3-5-6/h6H,1-5H2,(H,8,9)(H2,10,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-3 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50146811
((ethylamino)carbonylphosphonic acid | CHEMBL94348)Show InChI InChI=1S/C3H8NO4P/c1-2-4-3(5)9(6,7)8/h2H2,1H3,(H,4,5)(H2,6,7,8) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-9 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50146808
(CHEMBL318664 | [(1-ethylpropyl)amino]carbonylphosp...)Show InChI InChI=1S/C6H14NO4P/c1-3-5(4-2)7-6(8)12(9,10)11/h5H,3-4H2,1-2H3,(H,7,8)(H2,9,10,11) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50146801
((cyclohexylamino)carbonylphosphonic acid | CHEMBL3...)Show InChI InChI=1S/C7H14NO4P/c9-7(13(10,11)12)8-6-4-2-1-3-5-6/h6H,1-5H2,(H,8,9)(H2,10,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 55: 7875-82 (2012)
Article DOI: 10.1021/jm300981b BindingDB Entry DOI: 10.7270/Q23T9JBB |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50146808
(CHEMBL318664 | [(1-ethylpropyl)amino]carbonylphosp...)Show InChI InChI=1S/C6H14NO4P/c1-3-5(4-2)7-6(8)12(9,10)11/h5H,3-4H2,1-2H3,(H,7,8)(H2,9,10,11) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-2 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50146801
((cyclohexylamino)carbonylphosphonic acid | CHEMBL3...)Show InChI InChI=1S/C7H14NO4P/c9-7(13(10,11)12)8-6-4-2-1-3-5-6/h6H,1-5H2,(H,8,9)(H2,10,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-2 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50146817
((sec-butylamino)carbonylphosphonic acid | CHEMBL97...)Show InChI InChI=1S/C5H12NO4P/c1-3-4(2)6-5(7)11(8,9)10/h4H,3H2,1-2H3,(H,6,7)(H2,8,9,10) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Hebrew University of Jerusalem
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against recombinant matrix metalloprotease-2 was determined |
J Med Chem 47: 2826-32 (2004)
Article DOI: 10.1021/jm030386z BindingDB Entry DOI: 10.7270/Q2XS5W4C |
More data for this Ligand-Target Pair | |