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TargetBeta-2 adrenergic receptor and beta-3 adrenergic receptor
LigandBDBM50151721
Substrate/Competitorn/a
Meas. Tech.ChEMBL_302767
Ki 7.8±n/a nM
Citation Alikhani VBeer DBentley DBruce ICuenoud BMFairhurst RAGedeck PHaberthuer SHayden CJanus DJordan LLewis CSmithies KWissler E Long-chain formoterol analogues: an investigation into the effect of increasing amino-substituent chain length on the beta2-adrenoceptor activity. Bioorg Med Chem Lett 14:4705-10 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Beta-2 adrenergic receptor and beta-3 adrenergic receptor
Name:Beta-2 adrenergic receptor and beta-3 adrenergic receptor
Synonyms:ADRB2 | ADRB2R | B2AR | Beta-2 adrenergic receptor | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:n/a
Mol. Mass.:46461.69
Organism:Homo sapiens (Human)
Description:P07550
Residue:413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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  Blast E-value cutoff:
BDBM50151721
n/a
NameBDBM50151721
Synonyms:CHEMBL363260 | N-(2-Hydroxy-5-{(R)-1-hydroxy-2-[2-(4-phenethyloxy-phenyl)-ethylamino]-ethyl}-phenyl)-formamide
TypeSmall organic molecule
Emp. Form.C25H28N2O4
Mol. Mass.420.5008
SMILESO[C@@H](CNCCc1ccc(OCCc2ccccc2)cc1)c1ccc(O)c(NC=O)c1
Structure
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