| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Melanocortin receptor 3 |
|---|
| Ligand | BDBM50167673 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_302595 (CHEMBL839555) |
|---|
| Ki | 11250±n/a nM |
|---|
| Citation |  Tian, X; Field, T; Mazur, AW; Ebetino, FH; Wos, JA; Crossdoersen, D; Pinney, BB; Sheldon, RJ Design, synthesis, and evaluation of proline based melanocortin receptor ligands. Bioorg Med Chem Lett15:2819-23 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Melanocortin receptor 3 |
|---|
| Name: | Melanocortin receptor 3 |
|---|
| Synonyms: | MC3-R | MC3R | MC3R_HUMAN | Melanocortin MC3 | Melanocortin receptor (M3 and M4) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 36044.86 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P41968 |
|---|
| Residue: | 323 |
|---|
| Sequence: | MNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVI
LAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIF
DSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFI
VYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKG
AVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYA
FRSLELRNTFREILCGCNGMNLG
|
|
|
|---|
| BDBM50167673 |
|---|
| n/a |
|---|
| Name | BDBM50167673 |
|---|
| Synonyms: | (2S,4R)-4-Benzyl-1-[(S)-5-guanidino-2-(3-1H-imidazol-4-yl-propionylamino)-pentanoyl]-pyrrolidine-2-carboxylic acid benzylamide acetylamino ion |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C31H40N8O3 |
|---|
| Mol. Mass. | 572.7011 |
|---|
| SMILES | NC(=N)NCCC[C@H](NC(=O)CCc1cnc[nH]1)C(=O)N1C[C@H](Cc2ccccc2)C[C@H]1C(=O)NCc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
