| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocortin receptor 4 |
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| Ligand | BDBM50167682 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302572 (CHEMBL839533) |
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| Ki | >50000±n/a nM |
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| Citation |  Tian, X; Field, T; Mazur, AW; Ebetino, FH; Wos, JA; Crossdoersen, D; Pinney, BB; Sheldon, RJ Design, synthesis, and evaluation of proline based melanocortin receptor ligands. Bioorg Med Chem Lett15:2819-23 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocortin receptor 4 |
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| Name: | Melanocortin receptor 4 |
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| Synonyms: | MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R) |
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| Type: | Enzyme |
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| Mol. Mass.: | 36949.50 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P32245 |
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| Residue: | 332 |
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| Sequence: | MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLL
ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVN
IDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVS
GILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGAN
MKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPL
IYALRSQELRKTFKEIICCYPLGGLCDLSSRY
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| BDBM50167682 |
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| n/a |
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| Name | BDBM50167682 |
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| Synonyms: | (2S,4R)-4-Benzyl-1-[(R)-5-guanidino-2-(2-naphthalen-2-yl-acetylamino)-pentanoyl]-pyrrolidine-2-carboxylic acid benzylamide | CHEMBL193902 |
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| Type | Small organic molecule |
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| Emp. Form. | C37H42N6O3 |
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| Mol. Mass. | 618.7678 |
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| SMILES | NC(=N)NCCC[C@@H](NC(=O)Cc1ccc2ccccc2c1)C(=O)N1C[C@H](Cc2ccccc2)C[C@H]1C(=O)NCc1ccccc1 |
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| Structure | 
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