| Reaction Details |
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 | Report a problem with these data |
| Target | Growth hormone secretagogue receptor type 1 |
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| Ligand | BDBM50292224 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_306659 (CHEMBL831432) |
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| IC50 | 116±n/a nM |
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| Citation |  Tokunaga, T; Hume, WE; Nagamine, J; Kawamura, T; Taiji, M; Nagata, R Structure-activity relationships of the oxindole growth hormone secretagogues. Bioorg Med Chem Lett15:1789-92 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Growth hormone secretagogue receptor type 1 |
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| Name: | Growth hormone secretagogue receptor type 1 |
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| Synonyms: | GH-releasing peptide receptor | GHRP | GHS-R | GHSR | GHSR_HUMAN | Ghrelin Receptor (Growth Hormone Secretagogue Receptor Type 1) | Ghrelin receptor | Ghrelin receptor 1a (GHS-R1a) |
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| Type: | Receptor |
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| Mol. Mass.: | 41334.57 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Receptor binding studies use plasma membranes from LLC PK-1 cells transiently transfected with hGHSR1a. |
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| Residue: | 366 |
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| Sequence: | MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAG
NLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQ
FVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFV
LVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLW
RRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQI
SQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWT
ESSINT
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| BDBM50292224 |
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| n/a |
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| Name | BDBM50292224 |
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| Synonyms: | 1-(2-Diethylamino-ethyl)-3-hydroxy-2-oxo-3-phenyl-4-trifluoromethyl-2,3-dihydro-1H-indole-6-carboxylic acid amide | CHEMBL181312 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24F3N3O3 |
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| Mol. Mass. | 435.4395 |
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| SMILES | CCN(CC)CCN1C(=O)C(O)(c2c1cc(cc2C(F)(F)F)C(N)=O)c1ccccc1 |
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| Structure | 
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