Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Multidrug and toxin extrusion protein 1 (Mus musculus) | BDBM18512 (5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 145 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RIKEN Center for Life Science Technologies Curated by ChEMBL | Assay Description Inhibition of mouse Mate1 transfected in HEK293 cells assessed as uptake of [14C]-TEA preincubated for 15 mins by liquid scintillation counting analy... | Bioorg Med Chem 21: 7584-90 (2013) Article DOI: 10.1016/j.bmc.2013.10.041 BindingDB Entry DOI: 10.7270/Q2CN75C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 1 (Mus musculus) | BDBM18512 (5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RIKEN Center for Life Science Technologies Curated by ChEMBL | Assay Description Inhibition of mouse Oct1 transfected in HEK293 cells assessed as uptake of [14C]-TEA preincubated for 15 mins by liquid scintillation counting analys... | Bioorg Med Chem 21: 7584-90 (2013) Article DOI: 10.1016/j.bmc.2013.10.041 BindingDB Entry DOI: 10.7270/Q2CN75C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50292221 ((S)-3-(2,4-Dichloro-phenyl)-1-(2-diethylamino-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50366689 (GHRELIN) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50292225 ((S)-3-(2,5-Dichloro-phenyl)-1-(2-diethylamino-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50292228 ((S)-3-(2,3-Dichloro-phenyl)-1-(2-diethylamino-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50151162 ((S)-3-(2-Chloro-phenyl)-1-(2-diethylamino-ethyl)-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50151162 ((S)-3-(2-Chloro-phenyl)-1-(2-diethylamino-ethyl)-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50292230 ((S)-3-(2,6-Dichloro-phenyl)-1-(2-diethylamino-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50292223 ((R)-3-(3-Chloro-phenyl)-1-(2-diethylamino-ethyl)-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50292227 ((R)-1-(2-Diethylamino-ethyl)-3-hydroxy-3-(3-methox...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50292226 ((R)-3-(4-Chloro-phenyl)-1-(2-diethylamino-ethyl)-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50292229 ((R)-1-(2-Diethylamino-ethyl)-3-hydroxy-3-(4-methox...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 106 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50292224 (1-(2-Diethylamino-ethyl)-3-hydroxy-2-oxo-3-phenyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 116 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50292222 ((S)-1-(2-Diethylamino-ethyl)-3-hydroxy-3-(2-methox...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL | Assay Description Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparation | Bioorg Med Chem Lett 15: 1789-92 (2005) Article DOI: 10.1016/j.bmcl.2005.02.042 BindingDB Entry DOI: 10.7270/Q24J0FWD | |||||||||||
More data for this Ligand-Target Pair |