| Reaction Details |
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 | Report a problem with these data |
| Target | Genome polyprotein |
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| Ligand | BDBM50158818 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_305214 (CHEMBL832467) |
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| IC50 | 6400±n/a nM |
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| Citation |  Gordon, CP; Keller, PA Control of hepatitis C: a medicinal chemistry perspective. J Med Chem48:1-20 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Genome polyprotein |
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| Name: | Genome polyprotein |
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| Synonyms: | Hepatitis C virus NS3 protease/helicase | Hepatitis C virus serine protease, NS3/NS4A |
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| Type: | Protein |
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| Mol. Mass.: | 67067.41 |
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| Organism: | Hepatitis C virus |
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| Description: | A3EZI9 |
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| Residue: | 631 |
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| Sequence: | APITAYAQQTRGLLGCIITSLTGRDKNQVEGEVQIVSTAAQTFLATCINGVCWTVYHGAG
TRTIASSKGPVIQMYTNVDQDLVGWPAPQGARSLTPCTCGSSDLYLVTRHADVIPVRRRG
DGRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRAAVCTRGVAKAVDFIPVEGLETTMR
SPVFSDNSSPPAVPQSYQVAHLHAPTGSGKSTKVPAAYAAQGYKVLVLNPSVAATLGFGA
YMSKAHGIDPNIRTGVRTITTGSPITYSTYGKFLADGGCSGGAYDIIICDECHSTDATSI
LGIGTVLDQAETAGARLTVLATATPPGSVTVPHPNIEEVALSTTGEIPFYGKAIPLEAIK
GGRHLIFCHSKKKCDELAAKLVALGVNAVAYYRGLDVSVIPASGDVVVVATDALMTGFTG
DFDSVIDCNTCVTQTVDFSLDPTFTIETTTLPQDAVSRTQRRGRTGRGKPGIYRFVTPGE
RPSGMFDSSVLCECYDAGCAWYELTPAETTVRLRAYMNTPGLPVCQDHLEFWEGVFTGLT
HIDAHFLSQTKQSGENLPYLVAYQATVCARAQAPPPSWDQMWKCLIRLKPTLHGPTPLLY
RLGAVQNEITLTHPITKYIMTCMSADLEVVT
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| BDBM50158818 |
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| n/a |
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| Name | BDBM50158818 |
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| Synonyms: | CHEMBL333397 | {5-[4-Acetoxy-1-(4-bromo-phenyl)-but-(Z)-ylidene]-4-oxo-2-thioxo-thiazolidin-3-yl}-acetic acid | {5-[4-Acetoxy-1-(4-bromo-phenyl)-butylidene]-4-oxo-2-thioxo-thiazolidin-3-yl}-acetic acid(RD4-6205) |
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| Type | Small organic molecule |
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| Emp. Form. | C17H16BrNO5S2 |
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| Mol. Mass. | 458.347 |
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| SMILES | CC(=O)OCCC=C(c1sc(=S)n(CC(O)=O)c1O)c1ccc(Br)cc1 |w:6.5| |
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| Structure | 
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