| Reaction Details |
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 | Report a problem with these data |
| Target | Genome polyprotein |
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| Ligand | BDBM50158846 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_305077 (CHEMBL832708) |
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| IC50 | 7000±n/a nM |
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| Citation |  Gordon, CP; Keller, PA Control of hepatitis C: a medicinal chemistry perspective. J Med Chem48:1-20 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Genome polyprotein |
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| Name: | Genome polyprotein |
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| Synonyms: | Hepatitis C virus NS3 protease/helicase | Hepatitis C virus serine protease, NS3/NS4A |
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| Type: | Protein |
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| Mol. Mass.: | 67067.41 |
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| Organism: | Hepatitis C virus |
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| Description: | A3EZI9 |
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| Residue: | 631 |
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| Sequence: | APITAYAQQTRGLLGCIITSLTGRDKNQVEGEVQIVSTAAQTFLATCINGVCWTVYHGAG
TRTIASSKGPVIQMYTNVDQDLVGWPAPQGARSLTPCTCGSSDLYLVTRHADVIPVRRRG
DGRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRAAVCTRGVAKAVDFIPVEGLETTMR
SPVFSDNSSPPAVPQSYQVAHLHAPTGSGKSTKVPAAYAAQGYKVLVLNPSVAATLGFGA
YMSKAHGIDPNIRTGVRTITTGSPITYSTYGKFLADGGCSGGAYDIIICDECHSTDATSI
LGIGTVLDQAETAGARLTVLATATPPGSVTVPHPNIEEVALSTTGEIPFYGKAIPLEAIK
GGRHLIFCHSKKKCDELAAKLVALGVNAVAYYRGLDVSVIPASGDVVVVATDALMTGFTG
DFDSVIDCNTCVTQTVDFSLDPTFTIETTTLPQDAVSRTQRRGRTGRGKPGIYRFVTPGE
RPSGMFDSSVLCECYDAGCAWYELTPAETTVRLRAYMNTPGLPVCQDHLEFWEGVFTGLT
HIDAHFLSQTKQSGENLPYLVAYQATVCARAQAPPPSWDQMWKCLIRLKPTLHGPTPLLY
RLGAVQNEITLTHPITKYIMTCMSADLEVVT
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| BDBM50158846 |
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| n/a |
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| Name | BDBM50158846 |
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| Synonyms: | 2-(1-{4-[4-(3a,4,5,6,7,7a-hexahydro-1H-benzo[d]imidazol-2-yl)hexahydro-1-pyridinylmethyl]benzyl}hexahydro-4-pyridinyl)-3a,4,5,6,7,7a-hexahydro-1H-benzo[d]imidazole | CHEMBL366398 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H48N6 |
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| Mol. Mass. | 516.7637 |
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| SMILES | C(N1CCC(CC1)C1=NC2CCCCC2N1)c1ccc(CN2CCC(CC2)C2=NC3CCCCC3N2)cc1 |t:8,31| |
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| Structure | 
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