| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Deoxyuridine 5'-triphosphate nucleotidohydrolase |
|---|
| Ligand | BDBM50190545 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_320965 (CHEMBL885372) |
|---|
| Ki | 2800±n/a nM |
|---|
| Citation |  Nguyen, C; Kasinathan, G; Leal-Cortijo, I; Musso-Buendia, A; Kaiser, M; Brun, R; Ruiz-Pérez, LM; Johansson, NG; González-Pacanowska, D; Gilbert, IH Deoxyuridine triphosphate nucleotidohydrolase as a potential antiparasitic drug target. J Med Chem48:5942-54 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Deoxyuridine 5'-triphosphate nucleotidohydrolase |
|---|
| Name: | Deoxyuridine 5'-triphosphate nucleotidohydrolase |
|---|
| Synonyms: | dUTP pyrophosphatase |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 19574.43 |
|---|
| Organism: | Plasmodium falciparum |
|---|
| Description: | Q8II92 |
|---|
| Residue: | 173 |
|---|
| Sequence: | MHLKIVCLSDEVREMYKNHKTHHEGDSGLDLFIVKDEVLKPKSTTFVKLGIKAIALQYKS
NYYYKCEKSENKKKDDDKSNIVNTSFLLFPRSSISKTPLRLANSIGLIDAGYRGEIIAAL
DNTSDQEYHIKKNDKLVQLVSFTGEPLSFELVEELDETSRGEGGFGSTSNNKY
|
|
|
|---|
| BDBM50190545 |
|---|
| n/a |
|---|
| Name | BDBM50190545 |
|---|
| Synonyms: | 1-((2R,4S,5R)-4-hydroxy-5-((triphenylsilyloxy)methyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione | CHEMBL211446 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H26N2O5Si |
|---|
| Mol. Mass. | 486.5912 |
|---|
| SMILES | O[C@H]1C[C@@H](O[C@@H]1CO[Si](c1ccccc1)(c1ccccc1)c1ccccc1)n1ccc(=O)[nH]c1=O |
|---|
| Structure | 
|
|---|
Search and Browse
