| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM21219 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_325560 (CHEMBL860279) |
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| Ki | >10000±n/a nM |
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| Citation |  Novellino, E; Cosimelli, B; Ehlardo, M; Greco, G; Iadanza, M; Lavecchia, A; Rimoli, MG; Sala, A; Da Settimo, A; Primofiore, G; Da Settimo, F; Taliani, S; La Motta, C; Klotz, KN; Tuscano, D; Trincavelli, ML; Martini, C 2-(Benzimidazol-2-yl)quinoxalines: a novel class of selective antagonists at human A(1) and A(3) adenosine receptors designed by 3D database searching. J Med Chem48:8253-60 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36520.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30542 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
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| BDBM21219 |
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| n/a |
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| Name | BDBM21219 |
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| Synonyms: | 12-methyl-10-thia-1,4,5,6,8-pentaazatricyclo[7.3.0.0^{3,7}]dodeca-3(7),4,8-trien-2-one | 7-methyl-6,7-dihydro[1,3]thiazolo[3,2-a][1,2,3]triazolo[4,5-d]pyrimidin-9(3H)-one | CHEMBL445664 | triazolopyrimidinone, E |
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| Type | Small organic molecule |
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| Emp. Form. | C7H7N5OS |
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| Mol. Mass. | 209.228 |
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| SMILES | CC1CSc2nc3nn[nH]c3c(=O)n12 |
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| Structure | 
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