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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Muscarinic acetylcholine receptor M2 | ||
| Ligand | BDBM50176712 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_327856 (CHEMBL863986) | ||
| Ki | 3.2±n/a nM | ||
| Citation |  Starck, JP; Talaga, P; Quéré, L; Collart, P; Christophe, B; Lo Brutto, P; Jadot, S; Chimmanamada, D; Zanda, M; Wagner, A; Mioskowski, C; Massingham, R; Guyaux, M Potent anti-muscarinic activity in a novel series of quinuclidine derivatives. Bioorg Med Chem Lett16:373-7 (2005) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Muscarinic acetylcholine receptor M2 | |||
| Name: | Muscarinic acetylcholine receptor M2 | ||
| Synonyms: | ACM2_HUMAN | CHRM2 | Cholinergic, muscarinic M2 | Muscarinic acetylcholine receptor M2 and M4 | Muscarinic acetylcholine receptor M2 and M5 | RecName: Full=Muscarinic acetylcholine receptor M2 | ||
| Type: | GPCR | ||
| Mol. Mass.: | 51730.61 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P08172 | ||
| Residue: | 466 | ||
| Sequence: |
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| BDBM50176712 | |||
| n/a | |||
| Name | BDBM50176712 | ||
| Synonyms: | 1-cyclopentyl-3-(3-methoxyquinuclidin-3-yl)-1-phenylprop-2-yn-1-ol | CHEMBL200432 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H29NO2 | ||
| Mol. Mass. | 339.4712 | ||
| SMILES | COC1(CN2CCC1CC2)C#CC(O)(C1CCCC1)c1ccccc1 |THB:1:2:5.6:9.8,(26.6,5.4,;28.09,5.01,;28.5,3.51,;28.69,2.14,;30.23,2.79,;31.59,2.16,;31.32,3.55,;29.97,4.16,;30.04,5.8,;30.48,4.69,;27,3.12,;25.5,2.72,;24.01,2.33,;23.61,3.81,;24.41,.84,;23.43,-.35,;24.27,-1.64,;25.76,-1.25,;25.84,.29,;22.52,1.93,;21.42,3.02,;19.94,2.63,;19.53,1.13,;20.63,.04,;22.11,.44,)| | ||
| Structure | 
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