| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor |
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| Ligand | BDBM50151858 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_327858 (CHEMBL863988) |
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| Kd | 79±n/a nM |
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| Citation |  Starck, JP; Talaga, P; Quéré, L; Collart, P; Christophe, B; Lo Brutto, P; Jadot, S; Chimmanamada, D; Zanda, M; Wagner, A; Mioskowski, C; Massingham, R; Guyaux, M Potent anti-muscarinic activity in a novel series of quinuclidine derivatives. Bioorg Med Chem Lett16:373-7 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor |
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| Name: | Muscarinic acetylcholine receptor |
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| Synonyms: | GPM3 | Muscarinic acetylcholine receptor M3 |
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| Type: | n/a |
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| Mol. Mass.: | 66272.13 |
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| Organism: | Cavia porcellus |
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| Description: | n/a |
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| Residue: | 587 |
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| Sequence: | MTLHSNSTTLPLFPNISTSWIHSPSEAGLPPGTVTHFGSYNISQAAGNFSSLNGTTSDPL
GGHTIWQVVFIAFLTGFLALVTIIGNILVIVSFKVNKQLKHVNNYFLLSLADLIIGVISM
NLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTT
KRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYM
PVTIMTILYWRIYKETEKRTKELAGLQASGTEAETENFVHPTGSSRSCSSYELQQQSLKH
SSRRKYSRCHFWFATKSWKPNAGQMDQDHSSSDSWNNYDAAASLENSASDEEDIGSETRA
IYSIVLKLPGHSTILNSTKLPSSDNLQVPEEDLEPMDMERNASKPQTQKSMDDGGSFQKS
FSNLPIQLESTMDTAKTSDANSSVSKTMATLPLSFKEATLAKRFALRTRSQITKRKRMSL
IKEKRAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTYWNLGYWLCYINSTVNPVC
YALCNKTFRNTFKMLLLCQCDKRKRRKQQYQQRQSVIFHKRVPEQAL
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| BDBM50151858 |
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| n/a |
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| Name | BDBM50151858 |
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| Synonyms: | 4-(diethylamino)but-2-yn-1-yl (2S)-cyclohexyl(hydroxy)phenylacetate | CHEMBL185434 | OXYBUTYNIN | esoxybutynin |
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| Type | Small organic molecule |
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| Emp. Form. | C22H31NO3 |
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| Mol. Mass. | 357.4864 |
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| SMILES | CCN(CC)CC#CCOC(=O)[C@@](O)(C1CCCCC1)c1ccccc1 |
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| Structure | 
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