| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin K |
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| Ligand | BDBM50179545 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_340219 (CHEMBL865586) |
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| IC50 | 600±n/a nM |
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| Citation |  Shinozuka, T; Shimada, K; Matsui, S; Yamane, T; Ama, M; Fukuda, T; Taki, M; Naito, S 4-Aminophenoxyacetic acids as a novel class of reversible cathepsin K inhibitors. Bioorg Med Chem Lett16:1502-5 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin K |
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| Name: | Cathepsin K |
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| Synonyms: | CATK_HUMAN | CTSK | CTSO | CTSO2 | Cathepsin O | Cathepsin O2 | Cathepsin X |
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| Type: | Enzyme |
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| Mol. Mass.: | 36975.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43235 |
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| Residue: | 329 |
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| Sequence: | MWGLKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIH
NLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVD
YRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGG
YMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVA
RVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGE
NWGNKGYILMARNKNNACGIANLASFPKM
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| BDBM50179545 |
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| n/a |
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| Name | BDBM50179545 |
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| Synonyms: | CHEMBL203176 | N-(2-(4-methoxyphenylamino)ethyl)-4-methyl-2-(4-phenoxyphenoxy)pentanamide |
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| Type | Small organic molecule |
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| Emp. Form. | C27H32N2O4 |
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| Mol. Mass. | 448.554 |
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| SMILES | COc1ccc(NCCNC(=O)C(CC(C)C)Oc2ccc(Oc3ccccc3)cc2)cc1 |
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| Structure | 
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