Compile Data Set for Download or QSAR

Found 83 hits with Last Name = 'yamane' and Initial = 't'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50310094 ((7-carbamoyl-8H-indeno[1,2-d]thiazol-4-yloxy)methy...) Show SMILES NC(=O)c1ccc(OCP(O)(O)=O)c-2c1Cc1scnc-21 Show InChI InChI=1S/C12H11N2O5PS/c13-12(15)6-1-2-8(19-5-20(16,17)18)10-7(6)3-9-11(10)14-4-21-9/h1-2,4H,3,5H2,(H2,13,15)(H2,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Inhibition of human liver recombinant FBPase				Bioorg Med Chem Lett 20: 1004-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.056 BindingDB Entry DOI: 10.7270/Q2JW8F1D
					More data for this Ligand-Target Pair				3D Structure (crystal)
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50322036 (CHEMBL1173125 | Ethyl(2S,6S)-4-{[(7-carbamoyl-8H-i...) Show SMILES CCOC(=O)[C@H](C)NP(=O)(COc1ccc(C(N)=O)c2Cc3scnc3-c12)N[C@@H](C)C(=O)OCC |r| Show InChI InChI=1S/C22H29N4O7PS/c1-5-31-21(28)12(3)25-34(30,26-13(4)22(29)32-6-2)11-33-16-8-7-14(20(23)27)15-9-17-19(18(15)16)24-10-35-17/h7-8,10,12-13H,5-6,9,11H2,1-4H3,(H2,23,27)(H2,25,26,30)/t12-,13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human FBase				Bioorg Med Chem 18: 5346-51 (2010) Article DOI: 10.1016/j.bmc.2010.05.041 BindingDB Entry DOI: 10.7270/Q2TB17V0
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50322037 (CHEMBL1173126 | Ethyl(2S,6S)-2,6-dimethyl-4-({[7-(...) Show SMILES CCOC(=O)[C@H](C)NP(=O)(COc1ccc(C(=O)NC)c2Cc3scnc3-c12)N[C@@H](C)C(=O)OCC |r| Show InChI InChI=1S/C23H31N4O7PS/c1-6-32-22(29)13(3)26-35(31,27-14(4)23(30)33-7-2)12-34-17-9-8-15(21(28)24-5)16-10-18-20(19(16)17)25-11-36-18/h8-9,11,13-14H,6-7,10,12H2,1-5H3,(H,24,28)(H2,26,27,31)/t13-,14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human FBase				Bioorg Med Chem 18: 5346-51 (2010) Article DOI: 10.1016/j.bmc.2010.05.041 BindingDB Entry DOI: 10.7270/Q2TB17V0
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50310095 ((7-(methylcarbamoyl)-8H-indeno[1,2-d]thiazol-4-ylo...) Show SMILES CNC(=O)c1ccc(OCP(O)(O)=O)c-2c1Cc1scnc-21 Show InChI InChI=1S/C13H13N2O5PS/c1-14-13(16)7-2-3-9(20-6-21(17,18)19)11-8(7)4-10-12(11)15-5-22-10/h2-3,5H,4,6H2,1H3,(H,14,16)(H2,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Inhibition of human liver recombinant FBPase				Bioorg Med Chem Lett 20: 1004-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.056 BindingDB Entry DOI: 10.7270/Q2JW8F1D
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50179532 (1-(biphenyl-3-ylamino)-cyclohexanecarboxylic acid ...) Show SMILES CC[C@@H](CNc1ccc(OC)cc1)NC(=O)C1(CCCCC1)Nc1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C30H37N3O2/c1-3-25(22-31-26-15-17-28(35-2)18-16-26)32-29(34)30(19-8-5-9-20-30)33-27-14-10-13-24(21-27)23-11-6-4-7-12-23/h4,6-7,10-18,21,25,31,33H,3,5,8-9,19-20,22H2,1-2H3,(H,32,34)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Cathepsin K				Bioorg Med Chem Lett 16: 1502-5 (2006) Article DOI: 10.1016/j.bmcl.2005.12.053 BindingDB Entry DOI: 10.7270/Q2T154FS
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50310093 ((7-(pyrimidin-5-yl)-8H-indeno[1,2-d]thiazol-4-ylox...) Show SMILES OP(O)(=O)COc1ccc(c2Cc3scnc3-c12)-c1cncnc1 Show InChI InChI=1S/C15H12N3O4PS/c19-23(20,21)8-22-12-2-1-10(9-4-16-6-17-5-9)11-3-13-15(14(11)12)18-7-24-13/h1-2,4-7H,3,8H2,(H2,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Inhibition of human liver recombinant FBPase				Bioorg Med Chem Lett 20: 1004-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.056 BindingDB Entry DOI: 10.7270/Q2JW8F1D
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50179555 ((S)-2-(biphenyl-3-ylamino)-4-methyl-pentanoic acid...) Show SMILES CC[C@@H](CNc1ccc(OC)cc1)NC(=O)[C@H](CC(C)C)Nc1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C29H37N3O2/c1-5-24(20-30-25-14-16-27(34-4)17-15-25)32-29(33)28(18-21(2)3)31-26-13-9-12-23(19-26)22-10-7-6-8-11-22/h6-17,19,21,24,28,30-31H,5,18,20H2,1-4H3,(H,32,33)/t24-,28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Cathepsin K				Bioorg Med Chem Lett 16: 1502-5 (2006) Article DOI: 10.1016/j.bmcl.2005.12.053 BindingDB Entry DOI: 10.7270/Q2T154FS
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50179548 (1-(biphenyl-3-ylamino)-cyclohexanecarboxylic acid ...) Show SMILES CCC[C@@H](CNc1ccc(OC)cc1)NC(=O)C1(CCCCC1)Nc1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C31H39N3O2/c1-3-11-28(23-32-26-16-18-29(36-2)19-17-26)33-30(35)31(20-8-5-9-21-31)34-27-15-10-14-25(22-27)24-12-6-4-7-13-24/h4,6-7,10,12-19,22,28,32,34H,3,5,8-9,11,20-21,23H2,1-2H3,(H,33,35)/t28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Cathepsin K				Bioorg Med Chem Lett 16: 1502-5 (2006) Article DOI: 10.1016/j.bmcl.2005.12.053 BindingDB Entry DOI: 10.7270/Q2T154FS
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50179543 ((4-{(S)-2-[(S)-2-(biphenyl-3-ylamino)-4-methyl-pen...) Show SMILES CC[C@@H](CNc1ccc(OCC(O)=O)cc1)NC(=O)[C@H](CC(C)C)Nc1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C30H37N3O4/c1-4-24(19-31-25-13-15-27(16-14-25)37-20-29(34)35)33-30(36)28(17-21(2)3)32-26-12-8-11-23(18-26)22-9-6-5-7-10-22/h5-16,18,21,24,28,31-32H,4,17,19-20H2,1-3H3,(H,33,36)(H,34,35)/t24-,28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Cathepsin K				Bioorg Med Chem Lett 16: 1502-5 (2006) Article DOI: 10.1016/j.bmcl.2005.12.053 BindingDB Entry DOI: 10.7270/Q2T154FS
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50179547 (CHEMBL557986 | [4-((S)-2-{[1-(biphenyl-3-ylamino)-...) Show SMILES CC[C@@H](CNc1ccc(OCC(O)=O)cc1)NC(=O)C1(CCCCC1)Nc1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C31H37N3O4/c1-2-25(21-32-26-14-16-28(17-15-26)38-22-29(35)36)33-30(37)31(18-7-4-8-19-31)34-27-13-9-12-24(20-27)23-10-5-3-6-11-23/h3,5-6,9-17,20,25,32,34H,2,4,7-8,18-19,21-22H2,1H3,(H,33,37)(H,35,36)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Cathepsin K				Bioorg Med Chem Lett 16: 1502-5 (2006) Article DOI: 10.1016/j.bmcl.2005.12.053 BindingDB Entry DOI: 10.7270/Q2T154FS
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50179539 (CHEMBL383551 | [4-((S)-2-{[1-(biphenyl-3-ylamino)-...) Show SMILES CC[C@@H](CNc1ccc(OCC(=O)OC(C)(C)C)cc1)NC(=O)C1(CCCCC1)Nc1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C35H45N3O4/c1-5-28(24-36-29-17-19-31(20-18-29)41-25-32(39)42-34(2,3)4)37-33(40)35(21-10-7-11-22-35)38-30-16-12-15-27(23-30)26-13-8-6-9-14-26/h6,8-9,12-20,23,28,36,38H,5,7,10-11,21-22,24-25H2,1-4H3,(H,37,40)/t28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Cathepsin K				Bioorg Med Chem Lett 16: 1502-5 (2006) Article DOI: 10.1016/j.bmcl.2005.12.053 BindingDB Entry DOI: 10.7270/Q2T154FS
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50179542 (1-(biphenyl-3-ylamino)-cyclohexanecarboxylic acid ...) Show SMILES CCCC[C@@H](CNc1ccc(OC)cc1)NC(=O)C1(CCCCC1)Nc1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C32H41N3O2/c1-3-4-15-29(24-33-27-17-19-30(37-2)20-18-27)34-31(36)32(21-9-6-10-22-32)35-28-16-11-14-26(23-28)25-12-7-5-8-13-25/h5,7-8,11-14,16-20,23,29,33,35H,3-4,6,9-10,15,21-22,24H2,1-2H3,(H,34,36)/t29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Cathepsin K				Bioorg Med Chem Lett 16: 1502-5 (2006) Article DOI: 10.1016/j.bmcl.2005.12.053 BindingDB Entry DOI: 10.7270/Q2T154FS
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50179558 ((4-{(S)-2-[(S)-2-(biphenyl-3-ylamino)-4-methyl-pen...) Show SMILES CC[C@@H](CNc1ccc(OCC(=O)OC(C)(C)C)cc1)NC(=O)[C@H](CC(C)C)Nc1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C34H45N3O4/c1-7-27(22-35-28-16-18-30(19-17-28)40-23-32(38)41-34(4,5)6)37-33(39)31(20-24(2)3)36-29-15-11-14-26(21-29)25-12-9-8-10-13-25/h8-19,21,24,27,31,35-36H,7,20,22-23H2,1-6H3,(H,37,39)/t27-,31-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Cathepsin K				Bioorg Med Chem Lett 16: 1502-5 (2006) Article DOI: 10.1016/j.bmcl.2005.12.053 BindingDB Entry DOI: 10.7270/Q2T154FS
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50310086 ((7-chloro-8H-indeno[1,2-d]thiazol-4-yloxy)methylph...) Show SMILES OP(O)(=O)COc1ccc(Cl)c2Cc3scnc3-c12 Show InChI InChI=1S/C11H9ClNO4PS/c12-7-1-2-8(17-5-18(14,15)16)10-6(7)3-9-11(10)13-4-19-9/h1-2,4H,3,5H2,(H2,14,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Inhibition of human liver recombinant FBPase				Bioorg Med Chem Lett 20: 1004-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.056 BindingDB Entry DOI: 10.7270/Q2JW8F1D
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50310083 ((7-methyl-8H-indeno[1,2-d]thiazol-4-yloxy)methylph...) Show SMILES Cc1ccc(OCP(O)(O)=O)c-2c1Cc1scnc-21 Show InChI InChI=1S/C12H12NO4PS/c1-7-2-3-9(17-6-18(14,15)16)11-8(7)4-10-12(11)13-5-19-10/h2-3,5H,4,6H2,1H3,(H2,14,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Inhibition of human liver recombinant FBPase				Bioorg Med Chem Lett 20: 1004-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.056 BindingDB Entry DOI: 10.7270/Q2JW8F1D
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50322039 (CHEMBL1173572 | Ethyl(2S,6S)-2,6-dimethyl-4-{[(7-m...) Show SMILES CCOC(=O)[C@H](C)NP(=O)(COc1ccc(C)c2Cc3scnc3-c12)N[C@@H](C)C(=O)OCC |r| Show InChI InChI=1S/C22H30N3O6PS/c1-6-29-21(26)14(4)24-32(28,25-15(5)22(27)30-7-2)12-31-17-9-8-13(3)16-10-18-20(19(16)17)23-11-33-18/h8-9,11,14-15H,6-7,10,12H2,1-5H3,(H2,24,25,28)/t14-,15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human FBase				Bioorg Med Chem 18: 5346-51 (2010) Article DOI: 10.1016/j.bmc.2010.05.041 BindingDB Entry DOI: 10.7270/Q2TB17V0
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50310091 ((7-(pyridin-3-yl)-8H-indeno[1,2-d]thiazol-4-yloxy)...) Show SMILES OP(O)(=O)COc1ccc(c2Cc3scnc3-c12)-c1cccnc1 Show InChI InChI=1S/C16H13N2O4PS/c19-23(20,21)9-22-13-4-3-11(10-2-1-5-17-7-10)12-6-14-16(15(12)13)18-8-24-14/h1-5,7-8H,6,9H2,(H2,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Inhibition of human liver recombinant FBPase				Bioorg Med Chem Lett 20: 1004-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.056 BindingDB Entry DOI: 10.7270/Q2JW8F1D
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50310092 ((7-(pyridin-4-yl)-8H-indeno[1,2-d]thiazol-4-yloxy)...) Show SMILES OP(O)(=O)COc1ccc(c2Cc3scnc3-c12)-c1ccncc1 Show InChI InChI=1S/C16H13N2O4PS/c19-23(20,21)9-22-13-2-1-11(10-3-5-17-6-4-10)12-7-14-16(15(12)13)18-8-24-14/h1-6,8H,7,9H2,(H2,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Inhibition of human liver recombinant FBPase				Bioorg Med Chem Lett 20: 1004-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.056 BindingDB Entry DOI: 10.7270/Q2JW8F1D
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50310088 ((6,7-difluoro-8H-indeno[1,2-d]thiazol-4-yloxy)meth...) Show SMILES OP(O)(=O)COc1cc(F)c(F)c2Cc3scnc3-c12 Show InChI InChI=1S/C11H8F2NO4PS/c12-6-2-7(18-4-19(15,16)17)9-5(10(6)13)1-8-11(9)14-3-20-8/h2-3H,1,4H2,(H2,15,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Inhibition of human liver recombinant FBPase				Bioorg Med Chem Lett 20: 1004-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.056 BindingDB Entry DOI: 10.7270/Q2JW8F1D
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50322043 ((2S,2'S)-diethyl 2,2'-((5-(2-amino-5-isobutylthiaz...) Show SMILES CCOC(=O)[C@H](C)NP(=O)(N[C@@H](C)C(=O)OCC)c1ccc(o1)-c1nc(N)sc1CC(C)C |r| Show InChI InChI=1S/C21H33N4O6PS/c1-7-29-19(26)13(5)24-32(28,25-14(6)20(27)30-8-2)17-10-9-15(31-17)18-16(11-12(3)4)33-21(22)23-18/h9-10,12-14H,7-8,11H2,1-6H3,(H2,22,23)(H2,24,25,28)/t13-,14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human FBase				Bioorg Med Chem 18: 5346-51 (2010) Article DOI: 10.1016/j.bmc.2010.05.041 BindingDB Entry DOI: 10.7270/Q2TB17V0
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50322042 (CHEMBL1172936 | Ethyl4-{[(6,7-dimethyl-8H-indeno[1...) Show SMILES CCOC(=O)CNP(=O)(COc1cc(C)c(C)c2Cc3scnc3-c12)NCC(=O)OCC Show InChI InChI=1S/C21H28N3O6PS/c1-5-28-18(25)9-23-31(27,24-10-19(26)29-6-2)12-30-16-7-13(3)14(4)15-8-17-21(20(15)16)22-11-32-17/h7,11H,5-6,8-10,12H2,1-4H3,(H2,23,24,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human FBase				Bioorg Med Chem 18: 5346-51 (2010) Article DOI: 10.1016/j.bmc.2010.05.041 BindingDB Entry DOI: 10.7270/Q2TB17V0
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50322041 (CHEMBL1172935 | Isopropyl(2S,6S)-4-{[(6,7-dimethyl...) Show SMILES CC(C)OC(=O)[C@H](C)NP(=O)(COc1cc(C)c(C)c2Cc3scnc3-c12)N[C@@H](C)C(=O)OC(C)C |r| Show InChI InChI=1S/C25H36N3O6PS/c1-13(2)33-24(29)17(7)27-35(31,28-18(8)25(30)34-14(3)4)12-32-20-9-15(5)16(6)19-10-21-23(22(19)20)26-11-36-21/h9,11,13-14,17-18H,10,12H2,1-8H3,(H2,27,28,31)/t17-,18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human FBase				Bioorg Med Chem 18: 5346-51 (2010) Article DOI: 10.1016/j.bmc.2010.05.041 BindingDB Entry DOI: 10.7270/Q2TB17V0
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50293594 (5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...) Show SMILES CC(C)Cc1sc(N)nc1-c1ccc(o1)P(O)(O)=O Show InChI InChI=1S/C11H15N2O4PS/c1-6(2)5-8-10(13-11(12)19-8)7-3-4-9(17-7)18(14,15)16/h3-4,6H,5H2,1-2H3,(H2,12,13)(H2,14,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Inhibition of human liver recombinant FBPase				Bioorg Med Chem Lett 20: 1004-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.056 BindingDB Entry DOI: 10.7270/Q2JW8F1D
					More data for this Ligand-Target Pair				3D Structure (crystal)
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50317151 ((2S,2'S)-diethyl 2,2'-(((6,7-dimethyl-8H-indeno[1,...) Show SMILES CCOC(=O)[C@H](C)NP(=O)(COc1cc(C)c(C)c2Cc3scnc3-c12)N[C@@H](C)C(=O)OCC |r| Show InChI InChI=1S/C23H32N3O6PS/c1-7-30-22(27)15(5)25-33(29,26-16(6)23(28)31-8-2)12-32-18-9-13(3)14(4)17-10-19-21(20(17)18)24-11-34-19/h9,11,15-16H,7-8,10,12H2,1-6H3,(H2,25,26,29)/t15-,16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human FBase				Bioorg Med Chem 18: 5346-51 (2010) Article DOI: 10.1016/j.bmc.2010.05.041 BindingDB Entry DOI: 10.7270/Q2TB17V0
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50179559 ((S)-2-(biphenyl-3-ylamino)-4-methyl-pentanoic acid...) Show SMILES COc1ccc(NC[C@H](C)NC(=O)[C@H](CC(C)C)Nc2cccc(c2)-c2ccccc2)cc1 Show InChI InChI=1S/C28H35N3O2/c1-20(2)17-27(31-25-12-8-11-23(18-25)22-9-6-5-7-10-22)28(32)30-21(3)19-29-24-13-15-26(33-4)16-14-24/h5-16,18,20-21,27,29,31H,17,19H2,1-4H3,(H,30,32)/t21-,27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Cathepsin K				Bioorg Med Chem Lett 16: 1502-5 (2006) Article DOI: 10.1016/j.bmcl.2005.12.053 BindingDB Entry DOI: 10.7270/Q2T154FS
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50179551 (1-(biphenyl-3-ylamino)-cyclohexanecarboxylic acid ...) Show SMILES COc1ccc(NC[C@H](C)NC(=O)C2(CCCCC2)Nc2cccc(c2)-c2ccccc2)cc1 Show InChI InChI=1S/C29H35N3O2/c1-22(21-30-25-14-16-27(34-2)17-15-25)31-28(33)29(18-7-4-8-19-29)32-26-13-9-12-24(20-26)23-10-5-3-6-11-23/h3,5-6,9-17,20,22,30,32H,4,7-8,18-19,21H2,1-2H3,(H,31,33)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Cathepsin K				Bioorg Med Chem Lett 16: 1502-5 (2006) Article DOI: 10.1016/j.bmcl.2005.12.053 BindingDB Entry DOI: 10.7270/Q2T154FS
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50293594 (5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...) Show SMILES CC(C)Cc1sc(N)nc1-c1ccc(o1)P(O)(O)=O Show InChI InChI=1S/C11H15N2O4PS/c1-6(2)5-8-10(13-11(12)19-8)7-3-4-9(17-7)18(14,15)16/h3-4,6H,5H2,1-2H3,(H2,12,13)(H2,14,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human liver FBPase				Bioorg Med Chem Lett 19: 5909-12 (2009) Article DOI: 10.1016/j.bmcl.2009.08.081 BindingDB Entry DOI: 10.7270/Q23J3D22
					More data for this Ligand-Target Pair				3D Structure (crystal)
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50310087 ((6,7-dimethyl-8H-indeno[1,2-d]thiazol-4-yloxy)meth...) Show SMILES Cc1cc(OCP(O)(O)=O)c-2c(Cc3scnc-23)c1C Show InChI InChI=1S/C13H14NO4PS/c1-7-3-10(18-6-19(15,16)17)12-9(8(7)2)4-11-13(12)14-5-20-11/h3,5H,4,6H2,1-2H3,(H2,15,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Inhibition of human liver recombinant FBPase				Bioorg Med Chem Lett 20: 1004-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.056 BindingDB Entry DOI: 10.7270/Q2JW8F1D
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50310084 ((7-ethyl-8H-indeno[1,2-d]thiazol-4-yloxy)methylpho...) Show SMILES CCc1ccc(OCP(O)(O)=O)c-2c1Cc1scnc-21 Show InChI InChI=1S/C13H14NO4PS/c1-2-8-3-4-10(18-7-19(15,16)17)12-9(8)5-11-13(12)14-6-20-11/h3-4,6H,2,5,7H2,1H3,(H2,15,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Inhibition of human liver recombinant FBPase				Bioorg Med Chem Lett 20: 1004-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.056 BindingDB Entry DOI: 10.7270/Q2JW8F1D
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50179538 ((S)-2-(biphenyl-3-ylamino)-4-methyl-pentanoic acid...) Show SMILES CC[C@@H](CNc1ccc(OCc2nnn[nH]2)cc1)NC(=O)[C@H](CC(C)C)Nc1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C30H37N7O2/c1-4-24(19-31-25-13-15-27(16-14-25)39-20-29-34-36-37-35-29)33-30(38)28(17-21(2)3)32-26-12-8-11-23(18-26)22-9-6-5-7-10-22/h5-16,18,21,24,28,31-32H,4,17,19-20H2,1-3H3,(H,33,38)(H,34,35,36,37)/t24-,28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Cathepsin K				Bioorg Med Chem Lett 16: 1502-5 (2006) Article DOI: 10.1016/j.bmcl.2005.12.053 BindingDB Entry DOI: 10.7270/Q2T154FS
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50322040 (CHEMBL1173636 | Ethyl(2S,6S)-4-{[(7-ethyl-8H-inden...) Show SMILES CCOC(=O)[C@H](C)NP(=O)(COc1ccc(CC)c2Cc3scnc3-c12)N[C@@H](C)C(=O)OCC |r| Show InChI InChI=1S/C23H32N3O6PS/c1-6-16-9-10-18(20-17(16)11-19-21(20)24-12-34-19)32-13-33(29,25-14(4)22(27)30-7-2)26-15(5)23(28)31-8-3/h9-10,12,14-15H,6-8,11,13H2,1-5H3,(H2,25,26,29)/t14-,15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human FBase				Bioorg Med Chem 18: 5346-51 (2010) Article DOI: 10.1016/j.bmc.2010.05.041 BindingDB Entry DOI: 10.7270/Q2TB17V0
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50322038 (CHEMBL1173571 | Ethyl(2S,6S)-4-[({7-[(2,2-dimethyl...) Show SMILES CCOC(=O)[C@H](C)NP(=O)(COc1ccc(C(=O)NCC(C)(C)C)c2Cc3scnc3-c12)N[C@@H](C)C(=O)OCC |r| Show InChI InChI=1S/C27H39N4O7PS/c1-8-36-25(33)16(3)30-39(35,31-17(4)26(34)37-9-2)15-38-20-11-10-18(24(32)28-13-27(5,6)7)19-12-21-23(22(19)20)29-14-40-21/h10-11,14,16-17H,8-9,12-13,15H2,1-7H3,(H,28,32)(H2,30,31,35)/t16-,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human FBase				Bioorg Med Chem 18: 5346-51 (2010) Article DOI: 10.1016/j.bmc.2010.05.041 BindingDB Entry DOI: 10.7270/Q2TB17V0
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50310082 ((8H-indeno[1,2-d]thiazol-4-yloxy)methylphosphonic ...) Show SMILES OP(O)(=O)COc1cccc2Cc3scnc3-c12 Show InChI InChI=1S/C11H10NO4PS/c13-17(14,15)6-16-8-3-1-2-7-4-9-11(10(7)8)12-5-18-9/h1-3,5H,4,6H2,(H2,13,14,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Inhibition of human liver recombinant FBPase				Bioorg Med Chem Lett 20: 1004-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.056 BindingDB Entry DOI: 10.7270/Q2JW8F1D
					More data for this Ligand-Target Pair				3D Structure (crystal)
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50302495 (2-amino-4,5-dihydronaphtho[1,2-d][1,3]thiazol-8-yl...) Show SMILES Nc1nc-2c(CCc3ccc(OP(O)(O)=O)cc-23)s1 Show InChI InChI=1S/C11H11N2O4PS/c12-11-13-10-8-5-7(17-18(14,15)16)3-1-6(8)2-4-9(10)19-11/h1,3,5H,2,4H2,(H2,12,13)(H2,14,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human liver FBPase				Bioorg Med Chem Lett 19: 5909-12 (2009) Article DOI: 10.1016/j.bmcl.2009.08.081 BindingDB Entry DOI: 10.7270/Q23J3D22
					More data for this Ligand-Target Pair				3D Structure (crystal)
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50310085 ((7-fluoro-8H-indeno[1,2-d]thiazol-4-yloxy)methylph...) Show SMILES OP(O)(=O)COc1ccc(F)c2Cc3scnc3-c12 Show InChI InChI=1S/C11H9FNO4PS/c12-7-1-2-8(17-5-18(14,15)16)10-6(7)3-9-11(10)13-4-19-9/h1-2,4H,3,5H2,(H2,14,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Inhibition of human liver recombinant FBPase				Bioorg Med Chem Lett 20: 1004-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.056 BindingDB Entry DOI: 10.7270/Q2JW8F1D
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50302497 (CHEMBL572208 | Phosphoric acid mono-2-amino-5,6-di...) Show SMILES Nc1nc-2c(CCCc3ccc(OP(O)(O)=O)cc-23)s1 Show InChI InChI=1S/C12H13N2O4PS/c13-12-14-11-9-6-8(18-19(15,16)17)5-4-7(9)2-1-3-10(11)20-12/h4-6H,1-3H2,(H2,13,14)(H2,15,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human liver FBPase				Bioorg Med Chem Lett 19: 5909-12 (2009) Article DOI: 10.1016/j.bmcl.2009.08.081 BindingDB Entry DOI: 10.7270/Q23J3D22
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50310089 ((7-phenyl-8H-indeno[1,2-d]thiazol-4-yloxy)methylph...) Show SMILES OP(O)(=O)COc1ccc(c2Cc3scnc3-c12)-c1ccccc1 Show InChI InChI=1S/C17H14NO4PS/c19-23(20,21)10-22-14-7-6-12(11-4-2-1-3-5-11)13-8-15-17(16(13)14)18-9-24-15/h1-7,9H,8,10H2,(H2,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Inhibition of human liver recombinant FBPase				Bioorg Med Chem Lett 20: 1004-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.056 BindingDB Entry DOI: 10.7270/Q2JW8F1D
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50179549 ((S)-2-(biphenyl-3-ylamino)-4-methyl-pentanoic acid...) Show SMILES COc1ccc(NCCNC(=O)[C@H](CC(C)C)Nc2cccc(c2)-c2ccccc2)cc1 Show InChI InChI=1S/C27H33N3O2/c1-20(2)18-26(27(31)29-17-16-28-23-12-14-25(32-3)15-13-23)30-24-11-7-10-22(19-24)21-8-5-4-6-9-21/h4-15,19-20,26,28,30H,16-18H2,1-3H3,(H,29,31)/t26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Cathepsin K				Bioorg Med Chem Lett 16: 1502-5 (2006) Article DOI: 10.1016/j.bmcl.2005.12.053 BindingDB Entry DOI: 10.7270/Q2T154FS
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50310090 ((7-(pyridin-2-yl)-8H-indeno[1,2-d]thiazol-4-yloxy)...) Show SMILES OP(O)(=O)COc1ccc(c2Cc3scnc3-c12)-c1ccccn1 Show InChI InChI=1S/C16H13N2O4PS/c19-23(20,21)9-22-13-5-4-10(12-3-1-2-6-17-12)11-7-14-16(15(11)13)18-8-24-14/h1-6,8H,7,9H2,(H2,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co, Ltd Curated by ChEMBL					Assay Description Inhibition of human liver recombinant FBPase				Bioorg Med Chem Lett 20: 1004-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.056 BindingDB Entry DOI: 10.7270/Q2JW8F1D
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50302506 ((2-amino-4,5-dihydronaphtho[1,2-d]thiazol-8-yl)dif...) Show SMILES Nc1nc-2c(CCc3ccc(cc-23)C(F)(F)P(O)(O)=O)s1 Show InChI InChI=1S/C12H11F2N2O3PS/c13-12(14,20(17,18)19)7-3-1-6-2-4-9-10(8(6)5-7)16-11(15)21-9/h1,3,5H,2,4H2,(H2,15,16)(H2,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human liver FBPase				Bioorg Med Chem Lett 19: 5909-12 (2009) Article DOI: 10.1016/j.bmcl.2009.08.081 BindingDB Entry DOI: 10.7270/Q23J3D22
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50179556 ((S)-2-(3-cyclohexylphenylamino)-N-(2-(4-methoxyphe...) Show SMILES COc1ccc(NCCNC(=O)[C@H](CC(C)C)Nc2cccc(c2)C2CCCCC2)cc1 Show InChI InChI=1S/C27H39N3O2/c1-20(2)18-26(27(31)29-17-16-28-23-12-14-25(32-3)15-13-23)30-24-11-7-10-22(19-24)21-8-5-4-6-9-21/h7,10-15,19-21,26,28,30H,4-6,8-9,16-18H2,1-3H3,(H,29,31)/t26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Cathepsin K				Bioorg Med Chem Lett 16: 1502-5 (2006) Article DOI: 10.1016/j.bmcl.2005.12.053 BindingDB Entry DOI: 10.7270/Q2T154FS
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50179560 (CHEMBL383473 | N-(2-(4-methoxyphenylamino)ethyl)-4...) Show SMILES COc1ccc(NCCNC(=O)C(CC(C)C)Oc2cccc(Oc3ccccc3)c2)cc1 Show InChI InChI=1S/C27H32N2O4/c1-20(2)18-26(27(30)29-17-16-28-21-12-14-22(31-3)15-13-21)33-25-11-7-10-24(19-25)32-23-8-5-4-6-9-23/h4-15,19-20,26,28H,16-18H2,1-3H3,(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Cathepsin K				Bioorg Med Chem Lett 16: 1502-5 (2006) Article DOI: 10.1016/j.bmcl.2005.12.053 BindingDB Entry DOI: 10.7270/Q2T154FS
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (Homo sapiens (Human))	BDBM50302493 (2-amino-8H-indeno[1,2-d]thiazol-4-yl dihydrogen ph...) Show SMILES Nc1nc-2c(Cc3cccc(OP(O)(O)=O)c-23)s1 Show InChI InChI=1S/C10H9N2O4PS/c11-10-12-9-7(18-10)4-5-2-1-3-6(8(5)9)16-17(13,14)15/h1-3H,4H2,(H2,11,12)(H2,13,14,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human liver FBPase				Bioorg Med Chem Lett 19: 5909-12 (2009) Article DOI: 10.1016/j.bmcl.2009.08.081 BindingDB Entry DOI: 10.7270/Q23J3D22
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50179550 (1-(biphenyl-3-ylamino)-cyclohexanecarboxylic acid ...) Show SMILES COc1ccc(NC[C@@H](C)NC(=O)C2(CCCCC2)Nc2cccc(c2)-c2ccccc2)cc1 Show InChI InChI=1S/C29H35N3O2/c1-22(21-30-25-14-16-27(34-2)17-15-25)31-28(33)29(18-7-4-8-19-29)32-26-13-9-12-24(20-26)23-10-5-3-6-11-23/h3,5-6,9-17,20,22,30,32H,4,7-8,18-19,21H2,1-2H3,(H,31,33)/t22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Cathepsin K				Bioorg Med Chem Lett 16: 1502-5 (2006) Article DOI: 10.1016/j.bmcl.2005.12.053 BindingDB Entry DOI: 10.7270/Q2T154FS
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50179534 (1-(biphenyl-3-ylamino)-cyclohexanecarboxylic acid ...) Show SMILES COc1ccc(NCCNC(=O)C2(CCCCC2)Nc2cccc(c2)-c2ccccc2)cc1 Show InChI InChI=1S/C28H33N3O2/c1-33-26-15-13-24(14-16-26)29-19-20-30-27(32)28(17-6-3-7-18-28)31-25-12-8-11-23(21-25)22-9-4-2-5-10-22/h2,4-5,8-16,21,29,31H,3,6-7,17-20H2,1H3,(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Cathepsin K				Bioorg Med Chem Lett 16: 1502-5 (2006) Article DOI: 10.1016/j.bmcl.2005.12.053 BindingDB Entry DOI: 10.7270/Q2T154FS
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50113676 ((S)-benzyl 1-(2-(4-methoxyphenylamino)ethylamino)-...) Show SMILES COc1ccc(NCCNC(=O)[C@H](CC(C)C)NC(=O)OCc2ccccc2)cc1 Show InChI InChI=1S/C23H31N3O4/c1-17(2)15-21(26-23(28)30-16-18-7-5-4-6-8-18)22(27)25-14-13-24-19-9-11-20(29-3)12-10-19/h4-12,17,21,24H,13-16H2,1-3H3,(H,25,27)(H,26,28)/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Cathepsin K				Bioorg Med Chem Lett 16: 1502-5 (2006) Article DOI: 10.1016/j.bmcl.2005.12.053 BindingDB Entry DOI: 10.7270/Q2T154FS
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50179537 (2-(biphenyl-3-yloxy)-4-methyl-pentanoic acid [2-(4...) Show SMILES COc1ccc(NCCNC(=O)C(CC(C)C)Oc2cccc(c2)-c2ccccc2)cc1 Show InChI InChI=1S/C27H32N2O3/c1-20(2)18-26(27(30)29-17-16-28-23-12-14-24(31-3)15-13-23)32-25-11-7-10-22(19-25)21-8-5-4-6-9-21/h4-15,19-20,26,28H,16-18H2,1-3H3,(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Cathepsin K				Bioorg Med Chem Lett 16: 1502-5 (2006) Article DOI: 10.1016/j.bmcl.2005.12.053 BindingDB Entry DOI: 10.7270/Q2T154FS
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50179553 (1-(4-cyclohexylphenoxy)-N-(2-(4-methoxyphenylamino...) Show SMILES COc1ccc(NCCNC(=O)C2(CCCCC2)Oc2ccc(cc2)C2CCCCC2)cc1 Show InChI InChI=1S/C28H38N2O3/c1-32-25-16-12-24(13-17-25)29-20-21-30-27(31)28(18-6-3-7-19-28)33-26-14-10-23(11-15-26)22-8-4-2-5-9-22/h10-17,22,29H,2-9,18-21H2,1H3,(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Cathepsin K				Bioorg Med Chem Lett 16: 1502-5 (2006) Article DOI: 10.1016/j.bmcl.2005.12.053 BindingDB Entry DOI: 10.7270/Q2T154FS
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50179561 (2-(biphenyl-4-yloxy)-4-methyl-pentanoic acid [2-(4...) Show SMILES COc1ccc(NCCNC(=O)C(CC(C)C)Oc2ccc(cc2)-c2ccccc2)cc1 Show InChI InChI=1S/C27H32N2O3/c1-20(2)19-26(27(30)29-18-17-28-23-11-15-24(31-3)16-12-23)32-25-13-9-22(10-14-25)21-7-5-4-6-8-21/h4-16,20,26,28H,17-19H2,1-3H3,(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Cathepsin K				Bioorg Med Chem Lett 16: 1502-5 (2006) Article DOI: 10.1016/j.bmcl.2005.12.053 BindingDB Entry DOI: 10.7270/Q2T154FS
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50179540 (1-(biphenyl-4-ylamino)-cyclohexanecarboxylic acid ...) Show SMILES COc1ccc(NCCNC(=O)C2(CCCCC2)Nc2ccc(cc2)-c2ccccc2)cc1 Show InChI InChI=1S/C28H33N3O2/c1-33-26-16-14-24(15-17-26)29-20-21-30-27(32)28(18-6-3-7-19-28)31-25-12-10-23(11-13-25)22-8-4-2-5-9-22/h2,4-5,8-17,29,31H,3,6-7,18-21H2,1H3,(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Cathepsin K				Bioorg Med Chem Lett 16: 1502-5 (2006) Article DOI: 10.1016/j.bmcl.2005.12.053 BindingDB Entry DOI: 10.7270/Q2T154FS
					More data for this Ligand-Target Pair

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