| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50224350 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_450735 (CHEMBL901018) |
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| Ki | 80.2±n/a nM |
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| Citation |  Da Settimo, F; Primofiore, G; Taliani, S; Marini, AM; La Motta, C; Simorini, F; Salerno, S; Sergianni, V; Tuccinardi, T; Martinelli, A; Cosimelli, B; Greco, G; Novellino, E; Ciampi, O; Trincavelli, ML; Martini, C 5-amino-2-phenyl[1,2,3]triazolo[1,2-a][1,2,4]benzotriazin-1-one: a versatile scaffold to obtain potent and selective A3 adenosine receptor antagonists. J Med Chem50:5676-84 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36520.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30542 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
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| BDBM50224350 |
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| n/a |
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| Name | BDBM50224350 |
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| Synonyms: | 4-amino-8-chloro-2-phenyl-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalen-1-one | CHEMBL394064 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H10ClN5O |
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| Mol. Mass. | 311.726 |
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| SMILES | Nc1nc2ccc(Cl)cc2n2n1nc(-c1ccccc1)c2=O |
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| Structure | 
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