| Reaction Details |
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 | Report a problem with these data |
| Target | Pituitary adenylate cyclase-activating polypeptide type I receptor |
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| Ligand | BDBM50122102 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_469030 (CHEMBL949341) |
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| Ki | 72±n/a nM |
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| Citation |  Beebe, X; Darczak, D; Davis-Taber, RA; Uchic, ME; Scott, VE; Jarvis, MF; Stewart, AO Discovery and SAR of hydrazide antagonists of the pituitary adenylate cyclase-activating polypeptide (PACAP) receptor type 1 (PAC1-R). Bioorg Med Chem Lett18:2162-6 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Pituitary adenylate cyclase-activating polypeptide type I receptor |
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| Name: | Pituitary adenylate cyclase-activating polypeptide type I receptor |
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| Synonyms: | ADCYAP1R1 | PACR_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53307.50 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_498617 |
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| Residue: | 468 |
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| Sequence: | MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDN
ITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTE
DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN
YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN
DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIP
LFGIHYTVFAFSPENVSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKV
NRYFAVDFKHRHPSLASSGVNGGTQLSILSKSSSQIRMSGLPADNLAT
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| BDBM50122102 |
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| n/a |
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| Name | BDBM50122102 |
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| Synonyms: | 3-Cyano-4-hydroxy-benzoic acid [1-(2,3,5,6-tetramethyl-benzyl)-1H-indol-4-ylmethylene]-hydrazide | CHEMBL152640 | N'-((1-(2,3,5,6-tetramethylbenzyl)-1H-indol-4-yl)methylene)-3-cyano-4-hydroxybenzohydrazide |
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| Type | Small organic molecule |
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| Emp. Form. | C28H26N4O2 |
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| Mol. Mass. | 450.5316 |
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| SMILES | Cc1cc(C)c(C)c(Cn2ccc3c(\C=N\NC(=O)c4ccc(O)c(c4)C#N)cccc23)c1C |
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| Structure | 
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