| Reaction Details |
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 | Report a problem with these data |
| Target | Farnesyl diphosphate synthase |
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| Ligand | BDBM50374760 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_469917 (CHEMBL939264) |
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| IC50 | 515±n/a nM |
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| Citation |  Szajnman, SH; García Liñares, GE; Li, ZH; Jiang, C; Galizzi, M; Bontempi, EJ; Ferella, M; Moreno, SN; Docampo, R; Rodriguez, JB Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase. Bioorg Med Chem16:3283-90 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Farnesyl diphosphate synthase |
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| Name: | Farnesyl diphosphate synthase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 48827.21 |
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| Organism: | Trypanosoma cruzi |
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| Description: | ChEMBL_939177 |
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| Residue: | 425 |
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| Sequence: | MTAFACFPHSLFYSTRLPFFFFFFCVCVHCCLRYLCLLKCAYCCSDKNYFRPLNYFFYCL
YLAMASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVN
VAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFP
GVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDS
NKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLLVSEAAASVEMNLVER
VAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANY
GEKDPAKVAVVKRLYSKANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKT
HKRKK
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| BDBM50374760 |
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| n/a |
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| Name | BDBM50374760 |
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| Synonyms: | CHEMBL258540 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H17NO6P2 |
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| Mol. Mass. | 261.1498 |
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| SMILES | CC(C)CNCC(P(O)(O)=O)P(O)(O)=O |
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| Structure | 
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