| Reaction Details |
|---|
 | Report a problem with these data |
| Target | P2Y purinoceptor 4 |
|---|
| Ligand | BDBM50271187 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_552863 (CHEMBL958068) |
|---|
| EC50 | 90±n/a nM |
|---|
| Citation |  Ko, H; Carter, RL; Cosyn, L; Petrelli, R; de Castro, S; Besada, P; Zhou, Y; Cappellacci, L; Franchetti, P; Grifantini, M; Van Calenbergh, S; Harden, TK; Jacobson, KA Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists. Bioorg Med Chem16:6319-32 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| P2Y purinoceptor 4 |
|---|
| Name: | P2Y purinoceptor 4 |
|---|
| Synonyms: | NRU | P2P | P2RY4 | P2RY4_HUMAN | P2Y purinoceptor 4 | P2Y4 | Pyrimidinergic receptor P2Y4 | UNR | Uridine nucleotide receptor |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 40977.17 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_751027 |
|---|
| Residue: | 365 |
|---|
| Sequence: | MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLF
IFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLY
CSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKG
TTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSR
LRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSC
LDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTP
RADRL
|
|
|
|---|
| BDBM50271187 |
|---|
| n/a |
|---|
| Name | BDBM50271187 |
|---|
| Synonyms: | CHEMBL519835 | [dichloro({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(4-oxo-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl})methyl]phosphonic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H15Cl2N2O13P3S |
|---|
| Mol. Mass. | 567.124 |
|---|
| SMILES | O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)C(Cl)(Cl)P(O)(O)=O)n1ccc(=O)[nH]c1=S |r| |
|---|
| Structure | 
|
|---|
Search and Browse
