| Reaction Details |
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 | Report a problem with these data |
| Target | Myeloblastin |
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| Ligand | BDBM50270040 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_508142 (CHEMBL1004879) |
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| IC50 | >50000±n/a nM |
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| Citation |  Méthot, N; Rubin, J; Guay, D; Beaulieu, C; Ethier, D; Reddy, TJ; Riendeau, D; Percival, MD Inhibition of the activation of multiple serine proteases with a cathepsin C inhibitor requires sustained exposure to prevent pro-enzyme processing. J Biol Chem282:20836-46 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Myeloblastin |
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| Name: | Myeloblastin |
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| Synonyms: | Leukocyte proteinase 3 | MBN | PRTN3 | PRTN3_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27816.30 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1463425 |
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| Residue: | 256 |
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| Sequence: | MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTL
IHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVL
LIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTF
FCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYV
DWIRSTLRRVEAKGRP
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| BDBM50270040 |
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| n/a |
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| Name | BDBM50270040 |
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| Synonyms: | (S)-1-((1R,2R)-1-cyano-2-phenylcyclopropylamino)-1-oxo-3-(thiophen-2-yl)propan-2-aminium 2,2,2-trifluoroacetate | CHEMBL516292 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H18N3OS |
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| Mol. Mass. | 312.409 |
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| SMILES | [NH3+][C@@H](Cc1cccs1)C(=O)N[C@@]1(C[C@@H]1c1ccccc1)C#N |r| |
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| Structure | 
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