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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Sodium/hydrogen exchanger 1 | ||
| Ligand | BDBM50297575 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_583577 (CHEMBL1059092) | ||
| IC50 | 10.8±n/a nM | ||
| Citation |  Zhang, R; Dong, J; Xu, YG; Hua, WY; Wen, N; You, QD Synthesis and bioactivity of substituted indan-1-ylideneaminoguanidine derivatives. Eur J Med Chem44:3771-6 (2009) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Sodium/hydrogen exchanger 1 | |||
| Name: | Sodium/hydrogen exchanger 1 | ||
| Synonyms: | NHE-1 | Na(+)/H(+) exchanger 1 | Nhe1 | SL9A1_RAT | Slc9a1 | Solute carrier family 9 member 1 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 91655.00 | ||
| Organism: | Rattus norvegicus | ||
| Description: | ChEMBL_862370 | ||
| Residue: | 820 | ||
| Sequence: |
| ||
| BDBM50297575 | |||
| n/a | |||
| Name | BDBM50297575 | ||
| Synonyms: | 2-{[(1E)-2-(1H-1,3-benzodiazol-2-ylsulfanyl)-4,5,6-trimethoxy-2,3-dihydro-1H-inden-1-ylidene]amino}guanidine hydrochloride | CHEMBL557532 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H22N6O3S | ||
| Mol. Mass. | 426.492 | ||
| SMILES | COc1cc2C(=NN=C(N)N)C(Cc2c(OC)c1OC)Sc1nc2ccccc2[nH]1 |w:6.6,(.51,-14.95,;.5,-13.41,;-.83,-12.64,;-.84,-11.11,;-2.16,-10.35,;-2.48,-8.84,;-1.45,-7.7,;.06,-8.01,;1.08,-6.86,;2.59,-7.18,;.6,-5.4,;-4.01,-8.69,;-4.64,-10.09,;-3.49,-11.11,;-3.49,-12.64,;-4.83,-13.41,;-6.16,-12.64,;-2.16,-13.41,;-2.16,-14.95,;-3.5,-15.73,;-4.78,-7.36,;-6.32,-7.36,;-7.23,-6.1,;-8.71,-6.58,;-10.05,-5.82,;-11.38,-6.59,;-11.38,-8.14,;-10.05,-8.91,;-8.71,-8.14,;-7.23,-8.61,)| | ||
| Structure | 
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