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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Sodium/hydrogen exchanger 1 | ||
| Ligand | BDBM50297577 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_583577 (CHEMBL1059092) | ||
| IC50 | 1.73±n/a nM | ||
| Citation |  Zhang, R; Dong, J; Xu, YG; Hua, WY; Wen, N; You, QD Synthesis and bioactivity of substituted indan-1-ylideneaminoguanidine derivatives. Eur J Med Chem44:3771-6 (2009) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Sodium/hydrogen exchanger 1 | |||
| Name: | Sodium/hydrogen exchanger 1 | ||
| Synonyms: | NHE-1 | Na(+)/H(+) exchanger 1 | Nhe1 | SL9A1_RAT | Slc9a1 | Solute carrier family 9 member 1 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 91655.00 | ||
| Organism: | Rattus norvegicus | ||
| Description: | ChEMBL_862370 | ||
| Residue: | 820 | ||
| Sequence: |
| ||
| BDBM50297577 | |||
| n/a | |||
| Name | BDBM50297577 | ||
| Synonyms: | CHEMBL549392 | N''-[2-(1H-benzimidazol-2-ylthio)-2,3-dihydro-1H-inden-1-ylidene]carbonohydrazonic diamide dihydrochloride | ||
| Type | Small organic molecule | ||
| Emp. Form. | C17H16N6S | ||
| Mol. Mass. | 336.414 | ||
| SMILES | NC(N)=NN=C1C(Cc2ccccc12)Sc1nc2ccccc2[nH]1 |w:4.3,(18.41,3.83,;16.9,4.15,;16.42,5.61,;15.87,3,;14.36,3.31,;13.33,2.17,;11.8,2.32,;11.17,.92,;12.32,-.11,;12.32,-1.64,;13.65,-2.41,;14.98,-1.63,;14.98,-.11,;13.65,.66,;11.03,3.65,;9.49,3.65,;8.57,4.91,;7.1,4.43,;5.75,5.19,;4.43,4.42,;4.42,2.87,;5.76,2.1,;7.1,2.87,;8.58,2.39,)| | ||
| Structure | 
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