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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Sodium/hydrogen exchanger 1 | ||
| Ligand | BDBM50297583 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_583577 (CHEMBL1059092) | ||
| IC50 | 1.17±n/a nM | ||
| Citation |  Zhang, R; Dong, J; Xu, YG; Hua, WY; Wen, N; You, QD Synthesis and bioactivity of substituted indan-1-ylideneaminoguanidine derivatives. Eur J Med Chem44:3771-6 (2009) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Sodium/hydrogen exchanger 1 | |||
| Name: | Sodium/hydrogen exchanger 1 | ||
| Synonyms: | NHE-1 | Na(+)/H(+) exchanger 1 | Nhe1 | SL9A1_RAT | Slc9a1 | Solute carrier family 9 member 1 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 91655.00 | ||
| Organism: | Rattus norvegicus | ||
| Description: | ChEMBL_862370 | ||
| Residue: | 820 | ||
| Sequence: |
| ||
| BDBM50297583 | |||
| n/a | |||
| Name | BDBM50297583 | ||
| Synonyms: | CHEMBL560806 | N''-[2-(1H-benzimidazol-2-ylthio)-5-nitro-2,3-dihydro-1H-inden-1-ylidene]carbonohydrazonic diamide | ||
| Type | Small organic molecule | ||
| Emp. Form. | C17H15N7O2S | ||
| Mol. Mass. | 381.412 | ||
| SMILES | NC(N)=NN=C1C(Cc2cc(ccc12)[N+]([O-])=O)Sc1nc2ccccc2[nH]1 |w:4.3,(23.89,-33.56,;22.38,-33.25,;21.9,-31.79,;21.36,-34.4,;19.85,-34.09,;18.83,-35.25,;17.29,-35.09,;16.68,-36.51,;17.83,-37.52,;17.84,-39.05,;19.17,-39.81,;20.5,-39.03,;20.48,-37.5,;19.16,-36.75,;19.19,-41.36,;17.86,-42.14,;20.53,-42.12,;16.51,-33.77,;14.97,-33.78,;14.05,-32.53,;12.59,-33.02,;11.25,-32.25,;9.92,-33.03,;9.92,-34.57,;11.25,-35.34,;12.6,-34.56,;14.07,-35.03,)| | ||
| Structure | 
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