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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Sodium/hydrogen exchanger 1 | ||
| Ligand | BDBM50297567 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_583577 (CHEMBL1059092) | ||
| IC50 | 38±n/a nM | ||
| Citation |  Zhang, R; Dong, J; Xu, YG; Hua, WY; Wen, N; You, QD Synthesis and bioactivity of substituted indan-1-ylideneaminoguanidine derivatives. Eur J Med Chem44:3771-6 (2009) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Sodium/hydrogen exchanger 1 | |||
| Name: | Sodium/hydrogen exchanger 1 | ||
| Synonyms: | NHE-1 | Na(+)/H(+) exchanger 1 | Nhe1 | SL9A1_RAT | Slc9a1 | Solute carrier family 9 member 1 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 91655.00 | ||
| Organism: | Rattus norvegicus | ||
| Description: | ChEMBL_862370 | ||
| Residue: | 820 | ||
| Sequence: |
| ||
| BDBM50297567 | |||
| n/a | |||
| Name | BDBM50297567 | ||
| Synonyms: | CHEMBL561747 | N''-{6-fluoro-2-[(5-nitro-1H-benzimidazol-2-yl)thio]-2,3-dihydro-1H-inden-1-ylidene}carbonohydrazonic diamide hydrochloride | ||
| Type | Small organic molecule | ||
| Emp. Form. | C17H14FN7O2S | ||
| Mol. Mass. | 399.402 | ||
| SMILES | NC(N)=NN=C1C(Cc2ccc(F)cc12)Sc1nc2ccc(cc2[nH]1)[N+]([O-])=O |w:4.3,(38.61,-36.24,;37.1,-35.92,;36.62,-34.46,;36.07,-37.07,;34.56,-36.76,;33.53,-37.9,;32,-37.75,;31.37,-39.15,;32.52,-40.18,;32.52,-41.71,;33.85,-42.48,;35.18,-41.7,;36.52,-42.47,;35.18,-40.17,;33.86,-39.41,;31.23,-36.42,;29.69,-36.42,;28.78,-37.67,;27.3,-37.2,;25.96,-37.97,;24.63,-37.2,;24.63,-35.65,;25.95,-34.88,;27.3,-35.64,;28.78,-35.16,;23.29,-34.88,;23.28,-33.34,;21.95,-35.65,)| | ||
| Structure | 
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