Reaction Details | |||
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Target | Sodium/hydrogen exchanger 1 | ||
Ligand | BDBM50297571 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_583577 (CHEMBL1059092) | ||
IC50 | 1.74±n/a nM | ||
Citation | Zhang, R; Dong, J; Xu, YG; Hua, WY; Wen, N; You, QD Synthesis and bioactivity of substituted indan-1-ylideneaminoguanidine derivatives. Eur J Med Chem44:3771-6 (2009) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Sodium/hydrogen exchanger 1 | |||
Name: | Sodium/hydrogen exchanger 1 | ||
Synonyms: | NHE-1 | Na(+)/H(+) exchanger 1 | Nhe1 | SL9A1_RAT | Slc9a1 | Solute carrier family 9 member 1 | ||
Type: | PROTEIN | ||
Mol. Mass.: | 91655.00 | ||
Organism: | Rattus norvegicus | ||
Description: | ChEMBL_862370 | ||
Residue: | 820 | ||
Sequence: |
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BDBM50297571 | |||
n/a | |||
Name | BDBM50297571 | ||
Synonyms: | CHEMBL561343 | N''-{2-[(5-nitro-1H-benzimidazol-2-yl)thio]-2,3-dihydro-1H-inden-1-ylidene}carbonohydrazonic diamide hydrochloride | ||
Type | Small organic molecule | ||
Emp. Form. | C17H15N7O2S | ||
Mol. Mass. | 381.412 | ||
SMILES | NC(N)=NN=C1C(Cc2ccccc12)Sc1nc2ccc(cc2[nH]1)[N+]([O-])=O |w:4.3,(19.8,-22.61,;18.29,-22.3,;17.81,-20.83,;17.27,-23.45,;15.76,-23.13,;14.73,-24.28,;13.2,-24.13,;12.57,-25.53,;13.72,-26.55,;13.72,-28.08,;15.04,-28.85,;16.38,-28.08,;16.37,-26.55,;15.05,-25.79,;12.43,-22.79,;10.88,-22.79,;9.97,-24.05,;8.49,-23.57,;7.15,-24.34,;5.82,-23.57,;5.82,-22.02,;7.15,-21.25,;8.49,-22.02,;9.97,-21.54,;4.48,-21.26,;4.48,-19.71,;3.15,-22.03,)| | ||
Structure |