| Reaction Details |
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 | Report a problem with these data |
| Target | Ankyrin repeat and protein kinase domain-containing protein 1 |
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| Ligand | BDBM50326053 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_587171 (CHEMBL1060235) |
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| Kd | >10000±n/a nM |
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| Citation |  Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP A quantitative analysis of kinase inhibitor selectivity. Nat Biotechnol26:127-32 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ankyrin repeat and protein kinase domain-containing protein 1 |
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| Name: | Ankyrin repeat and protein kinase domain-containing protein 1 |
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| Synonyms: | ANKK1 | ANKK1_HUMAN | PKK2 | SGK288 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 84641.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_587171 |
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| Residue: | 765 |
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| Sequence: | MAADPTELRLGSLPVFTRDDFEGDWRLVASGGFSQVFQARHRRWRTEYAIKCAPCLPPDA
ASSDVNYLIEEAAKMKKIKFQHIVSIYGVCKQPLGIVMEFMANGSLEKVLSTHSLCWKLR
FRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQYIE
RSALRGMLSYIPPEMFLESNKAPGPKYDVYSFAIVIWELLTQKKPYSGFNMMMIIIRVAA
GMRPSLQPVSDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDITIETDILLSLLQSRVAVPE
SKALARKVSCKLSLRQPGEVNEDISQELMDSDSGNYLKRALQLSDRKNLVPRDEELCIYE
NKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGAD
ANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLL
VSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKV
RAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLA
AYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGW
TPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDV
QDGVSCTPLQLALRSRKQGIMSFLEGKEPSVATLGGSKPGAEMEI
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| BDBM50326053 |
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| n/a |
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| Name | BDBM50326053 |
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| Synonyms: | CHEMBL608533 | PKC-412 |
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| Type | Small organic molecule |
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| Emp. Form. | C35H30N4O4 |
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| Mol. Mass. | 570.6371 |
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| SMILES | CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1 |r| |
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| Structure | 
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