| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Caspase-2 |
|---|
| Ligand | BDBM50302107 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_600038 (CHEMBL1039231) |
|---|
| IC50 | 5000±n/a nM |
|---|
| Citation |  Kwan, JC; Eksioglu, EA; Liu, C; Paul, VJ; Luesch, H Grassystatins A-C from marine cyanobacteria, potent cathepsin E inhibitors that reduce antigen presentation. J Med Chem52:5732-47 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Caspase-2 |
|---|
| Name: | Caspase-2 |
|---|
| Synonyms: | CASP-2 | CASP2 | CASP2_HUMAN | Caspase-2 subunit p12 | Caspase-2 subunit p13 | Caspase-2 subunit p18 | ICH-1 protease | ICH-1L/1S | ICH1 | NEDD-2 | NEDD2 | Neural precursor cell expressed developmentally down-regulated protein 2 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 50688.29 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P42575 |
|---|
| Residue: | 452 |
|---|
| Sequence: | MAAPSAGSWSTFQHKELMAADRGRRILGVCGMHPHHQETLKKNRVVLAKQLLLSELLEHL
LEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQAFDAFCEALRETKQGHLEDMLLT
TLSGLQHVLPPLSCDYDLSLPFPVCESCPLYKKLRLSTDTVEHSLDNKDGPVCLQVKPCT
PEFYQTHFQLAYRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDV
HVLCDQTAQEMQEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLF
DNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHAGSPGCEESDAGKEKLPKMRLPT
RSDMICGYACLKGTAAMRNTKRGSWYIEALAQVFSERACDMHVADMLVKVNALIKDREGY
APGTEFHRCKEMSEYCSTLCRHLYLFPGHPPT
|
|
|
|---|
| BDBM50302107 |
|---|
| n/a |
|---|
| Name | BDBM50302107 |
|---|
| Synonyms: | CHEMBL567893 | Grassystatin A |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C58H95N9O16 |
|---|
| Mol. Mass. | 1174.4256 |
|---|
| SMILES | COC(=O)[C@@H]1CCCN1C(=O)[C@@H](Cc1ccccc1)N(C)C(=O)[C@H](C)NC(=O)[C@@H](NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](OC(=O)[C@@H](OC(=O)[C@H](C(C)C)N(C)C)C(C)C)C(C)C)[C@@H](C)O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
