| Reaction Details |
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 | Report a problem with these data |
| Target | Nucleoside triphosphate diphosphohydrolase 3 |
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| Ligand | BDBM50227032 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_612641 (CHEMBL1065678) |
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| Ki | 14300±n/a nM |
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| Citation |  Baqi, Y; Lee, SY; Iqbal, J; Ripphausen, P; Lehr, A; Scheiff, AB; Zimmermann, H; Bajorath, J; Müller, CE Development of potent and selective inhibitors of ecto-5'-nucleotidase based on an anthraquinone scaffold. J Med Chem53:2076-86 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Nucleoside triphosphate diphosphohydrolase 3 |
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| Name: | Nucleoside triphosphate diphosphohydrolase 3 |
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| Synonyms: | Ectonucleoside triphosphate diphosphohydrolase 3, isoform CRA_a | Protein Entpd3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 59110.31 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_612641 |
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| Residue: | 529 |
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| Sequence: | MFTVMTRQPCEQAGFRALSRTPAIVTLVVLLVSIVVLVTLTLIQIHHPQVLSPGLKYGIV
LDAGSSRTTVYVYQWPAEKENNTGVVSQTFRCSVKGSGISSYENNPQDAPKAFEDCMLKV
KEQVPKHLHESTRVYLGATAGMRLLRLQNETAAHEVLESIQSYFKSQPFDFRGAQIISGQ
EEGVYGWITANYIMGNFLEKNLWHMWVHPHGVDTTGALDLGGASTQISFVSEEKMEPNAS
DTVQVSLYGYTYTLYTHSFQCYGRNEAEKKFLAMLLQSPSTDANISNPCYPHGYSTTFTM
GHVFGSLCTEKQRPKSYNPSDTITFTGTGDPQLCREKVASVFDFSACQEQDACSFDGIYQ
PKVQGPFVAFAGFYYTASALNLSGSFSLTSFNDSSWDFCRHTWSELPSLLPRFDETYARS
YCFSAHYIYHLLINGYKFTEATWPQIRFEKEVGNSSIAWSLGYMLSLTNQIPAGSPLIQL
PIQPPVFMGVLAFFTAIALLCLAFLFYLCSAFRTKERSENAFDQAVDSD
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| BDBM50227032 |
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| n/a |
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| Name | BDBM50227032 |
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| Synonyms: | CHEMBL256057 | acid blue 25 | sodium 1-amino-9,10-dioxo-4-(phenylamino)-9,10-dihydroanthracene-2-sulfonate |
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| Type | Small organic molecule |
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| Emp. Form. | C20H13N2O5S |
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| Mol. Mass. | 393.393 |
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| SMILES | Nc1c2C(=O)c3ccccc3C(=O)c2c(Nc2ccccc2)cc1S([O-])(=O)=O |
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| Structure | 
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