| Reaction Details |
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 | Report a problem with these data |
| Target | Orotidine 5'-phosphate decarboxylase |
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| Ligand | BDBM50378784 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_639015 (CHEMBL1166153) |
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| Temperature | 298.15±n/a K |
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| Ki | 5±n/a nM |
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| Comments | extracted |
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| Citation |  Meza-Avina, ME; Wei, L; Liu, Y; Poduch, E; Bello, AM; Mishra, RK; Pai, EF; Kotra, LP Structural determinants for the inhibitory ligands of orotidine-5'-monophosphate decarboxylase. Bioorg Med Chem18:4032-41 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Orotidine 5'-phosphate decarboxylase |
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| Name: | Orotidine 5'-phosphate decarboxylase |
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| Synonyms: | Orotidine phosphate decarboxylase | PYRF_YEAST | URA3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 29241.18 |
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| Organism: | Saccharomyces cerevisiae |
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| Description: | ChEMBL_639015 |
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| Residue: | 267 |
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| Sequence: | MSKATYKERAATHPSPVAAKLFNIMHEKQTNLCASLDVRTTKELLELVEALGPKICLLKT
HVDILTDFSMEGTVKPLKALSAKYNFLLFEDRKFADIGNTVKLQYSAGVYRIAEWADITN
AHGVVGPGIVSGLKQAAEEVTKEPRGLLMLAELSCKGSLATGEYTKGTVDIAKSDKDFVI
GFIAQRDMGGRDEGYDWLIMTPGVGLDDKGDALGQQYRTVDDVVSTGSDIIIVGRGLFAK
GRDAKVEGERYRKAGWEAYLRRCGQQN
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| BDBM50378784 |
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| n/a |
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| Name | BDBM50378784 |
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| Synonyms: | CHEMBL1164953 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H14N3O9P |
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| Mol. Mass. | 339.1959 |
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| SMILES | NC(=O)c1[nH]nc([C@@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]2O)c1O |r| |
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| Structure | 
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