| Reaction Details |
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 | Report a problem with these data |
| Target | Ribosyldihydronicotinamide dehydrogenase [quinone] |
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| Ligand | BDBM50322046 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_642470 (CHEMBL1175843) |
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| IC50 | 270±n/a nM |
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| Citation |  Sun, B; Hoshino, J; Jermihov, K; Marler, L; Pezzuto, JM; Mesecar, AD; Cushman, M Design, synthesis, and biological evaluation of resveratrol analogues as aromatase and quinone reductase 2 inhibitors for chemoprevention of cancer. Bioorg Med Chem18:5352-66 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ribosyldihydronicotinamide dehydrogenase [quinone] |
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| Name: | Ribosyldihydronicotinamide dehydrogenase [quinone] |
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| Synonyms: | Metallothionein-3 | NMOR2 | NQO2 | NQO2_HUMAN | NRH dehydrogenase [quinone] 2 | NRH:quinone oxidoreductase 2 | QR2 | Quinone reductase 2 | Quinone reductase 2 (NQO2) | Ribosyldihydronicotinamide dehydrogenase [quinone] |
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| Type: | Protein |
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| Mol. Mass.: | 25917.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P16083 |
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| Residue: | 231 |
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| Sequence: | MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTL
SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRV
LCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC
GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ
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| BDBM50322046 |
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| n/a |
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| Name | BDBM50322046 |
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| Synonyms: | 3,4,5-Trimethoxy-4'-amino-trans-stilbene | 4-[2-(3,4,5-Trimethoxy-phenyl)-vinyl]-phenylamine | CHEMBL87477 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H19NO3 |
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| Mol. Mass. | 285.3377 |
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| SMILES | COc1cc(\C=C\c2ccc(N)cc2)cc(OC)c1OC |
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| Structure | 
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