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Target1-deoxy-D-xylulose 5-phosphate reductoisomerase
LigandBDBM50181154
Substrate/Competitorn/a
Meas. Tech.ChEMBL_702118 (CHEMBL1655348)
IC50 59±n/a nM
Citation Deng, LEndo, KKato, MCheng, GYajima, SSong, Y Structures of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase/Lipophilic Phosphonate Complexes. ACS Med Chem Lett2:165-170 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
1-deoxy-D-xylulose 5-phosphate reductoisomerase
Name:1-deoxy-D-xylulose 5-phosphate reductoisomerase
Synonyms:1-Deoxy-D-xylulose 5-phosphate reductoisomerase (DXP) | 1-Deoxyxylulose 5-phosphate reductoisomerase (DXR) | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) | 2-C-methyl-D-erythritol 4-phosphate synthase | DXP reductoisomerase | DXR_ECOLI | dxr | ispC | yaeM
Type:Protein
Mol. Mass.:43384.52
Organism:Escherichia coli
Description:P45568
Residue:398
Sequence:
MKQLTILGSTGSIGCSTLDVVRHNPEHFRVVALVAGKNVTRMVEQCLEFSPRYAVMDDEA
SAKLLKTMLQQQGSRTEVLSGQQAACDMAALEDVDQVMAAIVGAAGLLPTLAAIRAGKTI
LLANKESLVTCGRLFMDAVKQSKAQLLPVDSEHNAIFQSLPQPIQHNLGYADLEQNGVVS
ILLTGSGGPFRETPLRDLATMTPDQACRHPNWSMGRKISVDSATMMNKGLEYIEARWLFN
ASASQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDMRTPIAHTMAWPNRVNSGVKPLDFC
KLSALTFAAPDYDRYPCLKLAMEAFEQGQAATTALNAANEITVAAFLAQQIRFTDIAALN
LSVLEKMDMREPQCVDDVLSVDANAREVARKEVMRLAS
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BDBM50181154
n/a
NameBDBM50181154
Synonyms:1-(3,4-dichlorophenyl)-3-(N-hydroxyformamido)propylphosphonic acid | CHEMBL204106 | ammonium 1-(3,4-dichlorophenyl)-3-(N-hydroxyformamido)propylphosphonate
TypeSmall organic molecule
Emp. Form.C10H12Cl2NO5P
Mol. Mass.328.086
SMILESON(CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O)C=O
Structure
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