| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 6 |
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| Ligand | BDBM50343142 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_745333 (CHEMBL1775408) |
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| IC50 | >50000±n/a nM |
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| Citation |  Chen, L; Zhou, B; Zhang, S; Wu, L; Wang, Y; Franzblau, SG; Zhang, ZY Identification and characterization of novel inhibitors of mPTPB, an essential virulent phosphatase from Mycobacterium tuberculosis. ACS Med Chem Lett1:355-359 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein phosphatase 6 |
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| Name: | Dual specificity protein phosphatase 6 |
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| Synonyms: | DUS6_HUMAN | DUSP6 | Dual specificity protein phosphatase PYST1 | MAP kinase phosphatase 3 | MKP3 | Mitogen-activated protein kinase phosphatase 3 | PYST1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42305.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1476409 |
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| Residue: | 381 |
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| Sequence: | MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPG
IMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESVLGLLLK
KLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ
QLYFTTPSNQNVYQVDSLQST
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| BDBM50343142 |
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| n/a |
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| Name | BDBM50343142 |
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| Synonyms: | CHEMBL1773168 | N-(4-butylphenyl)-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide |
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| Type | Small organic molecule |
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| Emp. Form. | C21H20N2O3S |
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| Mol. Mass. | 380.46 |
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| SMILES | CCCCc1ccc(NS(=O)(=O)c2ccc3NC(=O)c4cccc2c34)cc1 |
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| Structure | 
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