| Reaction Details |
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 | Report a problem with these data |
| Target | Atypical chemokine receptor 3 |
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| Ligand | BDBM50380115 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_811526 (CHEMBL2013880) |
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| Ki | 1584.89±n/a nM |
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| Citation |  Wijtmans, M; Maussang, D; Sirci, F; Scholten, DJ; Canals, M; Mujic-Delic, A; Chong, M; Chatalic, KL; Custers, H; Janssen, E; de Graaf, C; Smit, MJ; de Esch, IJ; Leurs, R Synthesis, modeling and functional activity of substituted styrene-amides as small-molecule CXCR7 agonists. Eur J Med Chem51:184-92 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Atypical chemokine receptor 3 |
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| Name: | Atypical chemokine receptor 3 |
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| Synonyms: | ACKR3 | ACKR3_HUMAN | C-X-C chemokine receptor type 7 | C-X-C chemokine receptor type 7 (CXCR7) | CMKOR1 | CXC-R7 | CXCR-7 | CXCR7 | Chemokine orphan receptor 1 | G-protein coupled receptor 159 | G-protein coupled receptor RDC1 homolog | GPR159 | RDC-1 | RDC1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 41498.84 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P25106 |
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| Residue: | 362 |
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| Sequence: | MDLHLFDYSEPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMI
ANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVT
HLIFSINLFGSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDT
YYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAIS
ASSDQEKHSSRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVT
QCLSLVHCCVNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQS
TK
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| BDBM50380115 |
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| n/a |
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| Name | BDBM50380115 |
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| Synonyms: | CHEMBL2013233 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H30F2N2O3 |
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| Mol. Mass. | 456.5248 |
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| SMILES | CN1CCCC1CCN(C\C(C)=C\c1ccc(F)cc1F)C(=O)c1ccc2OCCOc2c1 |
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| Structure | 
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