Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetMu-type opioid receptor
LigandBDBM50381674
Substrate/Competitorn/a
Meas. Tech.ChEMBL_816181
Ki>10000±n/a nM
Citation Lovell KMVasiljevik TAraya JJLozama APrevatt-Smith KMDay VWDersch CMRothman RBButelman ERKreek MJPrisinzano TE Semisynthetic neoclerodanes as kappa opioid receptor probes. Bioorg Med Chem 20:3100-10 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:M-OR-1 | MOP | MOR-1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | hMOP | mu-type opioid receptor isoform MOR-1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44789.51
Organism:Homo sapiens (Human)
Description:P35372
Residue:400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50381674
n/a
NameBDBM50381674
Synonyms:CHEMBL2022295
TypeSmall organic molecule
Emp. Form.C26H30O9
Mol. Mass.486.511
SMILESCOC(=O)[C@@H]1C[C@H](OC(C)=O)C(=O)[C@H]2[C@@]1(C)CC[C@H]1C(=O)O[C@@H](C[C@]21C)C(=O)c1ccc(O)cc1 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: