| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50083922 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_818427 (CHEMBL2034747) |
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| Ki | 728±n/a nM |
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| Citation |  Taliani, S; Pugliesi, I; Barresi, E; Simorini, F; Salerno, S; La Motta, C; Marini, AM; Cosimelli, B; Cosconati, S; Di Maro, S; Marinelli, L; Daniele, S; Trincavelli, ML; Greco, G; Novellino, E; Martini, C; Da Settimo, F 3-aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A2B adenosine receptor antagonists. J Med Chem55:1490-9 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36520.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30542 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
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| BDBM50083922 |
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| n/a |
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| Name | BDBM50083922 |
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| Synonyms: | 3-Phenyl-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-4-one | CHEMBL7113 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H10N4O |
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| Mol. Mass. | 262.2661 |
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| SMILES | O=c1c(nnc2[nH]c3ccccc3n12)-c1ccccc1 |
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| Structure | 
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