| Reaction Details |
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 | Report a problem with these data |
| Target | Fibroblast growth factor 1 |
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| Ligand | BDBM50388342 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_829712 (CHEMBL2061152) |
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| Kd | 0.44±n/a nM |
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| Citation |  Ferro, V; Liu, L; Johnstone, KD; Wimmer, N; Karoli, T; Handley, P; Rowley, J; Dredge, K; Li, CP; Hammond, E; Davis, K; Sarimaa, L; Harenberg, J; Bytheway, I Discovery of PG545: a highly potent and simultaneous inhibitor of angiogenesis, tumor growth, and metastasis. J Med Chem55:3804-13 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Fibroblast growth factor 1 |
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| Name: | Fibroblast growth factor 1 |
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| Synonyms: | Acidic fibroblast growth factor | Beta-endothelial cell growth factor | ECGF-beta | FGF1 | FGF1_HUMAN | FGFA | Fibroblast growth factor 1 (FGF-1) | HBGF-1 | Heparin-binding growth factor 1 | aFGF |
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| Type: | Protein |
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| Mol. Mass.: | 17461.01 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P05230 |
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| Residue: | 155 |
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| Sequence: | MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQ
LSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEK
NWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD
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| BDBM50388342 |
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| n/a |
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| Name | BDBM50388342 |
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| Synonyms: | CHEMBL2059242 |
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| Type | Small organic molecule |
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| Emp. Form. | C45H70NO61S13 |
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| Mol. Mass. | 2017.86 |
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| SMILES | CCCCCCCCCCCCCCCCCC(=O)NCCCO[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| |
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| Structure | 
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