Reaction Details | |||
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Target | 4,4'-diapophytoene synthase | ||
Ligand | BDBM50388398 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_829914 (CHEMBL2061562) | ||
Ki | 360±n/a nM | ||
Citation | Lin, FY; Liu, YL; Li, K; Cao, R; Zhu, W; Axelson, J; Pang, R; Oldfield, E Head-to-head prenyl tranferases: anti-infective drug targets. J Med Chem55:4367-72 (2012) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
4,4'-diapophytoene synthase | |||
Name: | 4,4'-diapophytoene synthase | ||
Synonyms: | CRTM_STAAU | Dehydrosqualene synthase | crtM | ||
Type: | PROTEIN | ||
Mol. Mass.: | 34309.10 | ||
Organism: | Staphylococcus aureus | ||
Description: | ChEMBL_1352846 | ||
Residue: | 287 | ||
Sequence: |
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BDBM50388398 | |||
n/a | |||
Name | BDBM50388398 | ||
Synonyms: | CHEMBL561057 | SQ-109 | ||
Type | Small organic molecule | ||
Emp. Form. | C22H38N2 | ||
Mol. Mass. | 330.5505 | ||
SMILES | CC(C)=CCC\C(C)=C\CNCCNC1C2CC3CC(C2)CC1C3 |TLB:18:19:16.17.23:14,23:22:20:16.17.18,13:14:20:16.17.18,13:14:16.17.23:20.19.21,THB:18:17:14:20.19.21,23:17:20:22.14.21,21:19:16:23.22.14,21:22:16:20.18.19,13:14:16:20.18.19,(-5.14,2.27,;-5.13,1.44,;-5.84,1.02,;-4.41,1.04,;-3.7,1.46,;-2.98,1.06,;-2.28,1.48,;-2.29,2.3,;-1.56,1.08,;-.85,1.5,;-.13,1.09,;.58,1.51,;1.3,1.11,;2.04,1.48,;2.72,1.02,;2.74,.22,;2.11,-.47,;2.91,-.24,;3.67,-.52,;4.2,.17,;3.46,-.03,;4.19,.99,;3.44,1.28,;2.89,.61,)| | ||
Structure |