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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Dipeptidyl peptidase 4 | ||
| Ligand | BDBM50391474 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_849436 (CHEMBL2149437) | ||
| IC50 | 676±n/a nM | ||
| Citation |  Ikuma, Y; Hochigai, H; Kimura, H; Nunami, N; Kobayashi, T; Uchiyama, K; Furuta, Y; Sakai, M; Horiguchi, M; Masui, Y; Okazaki, K; Sato, Y; Nakahira, H Discovery of 3H-imidazo[4,5-c]quinolin-4(5H)-ones as potent and selective dipeptidyl peptidase IV (DPP-4) inhibitors. Bioorg Med Chem20:5864-83 (2012) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Dipeptidyl peptidase 4 | |||
| Name: | Dipeptidyl peptidase 4 | ||
| Synonyms: | ACT3 | ADCP-I | Activation molecule 3 | Adenosine deaminase complexing protein | CD26 | CD_antigen=CD26 | DPP IV | DPP4 | DPP4_BOVIN | Dipeptidyl peptidase 4 | Dipeptidyl peptidase 4 membrane form | Dipeptidyl peptidase 4 soluble form | Dipeptidyl peptidase IV | Dipeptidyl peptidase IV membrane form | Dipeptidyl peptidase IV soluble form | T-cell activation antigen CD26 | WC10 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 88365.89 | ||
| Organism: | Bos taurus | ||
| Description: | ChEMBL_849436 | ||
| Residue: | 765 | ||
| Sequence: |
| ||
| BDBM50391474 | |||
| n/a | |||
| Name | BDBM50391474 | ||
| Synonyms: | CHEMBL2147197 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C15H22N6O2 | ||
| Mol. Mass. | 318.3742 | ||
| SMILES | CC(C)=CCn1c(nc2n(C)c(=O)[nH]c(=O)c12)N1CCNCC1 |(-.09,4.19,;-1.46,3.49,;-2.76,4.33,;-1.54,1.94,;-2.92,1.24,;-3,-.31,;-2.06,-1.52,;-2.92,-2.8,;-4.4,-2.36,;-5.7,-3.17,;-5.65,-4.72,;-7.05,-2.44,;-8.37,-3.26,;-7.1,-.91,;-5.8,-.11,;-5.84,1.44,;-4.45,-.83,;-.52,-1.47,;.29,-2.78,;1.83,-2.73,;2.55,-1.37,;1.75,-.07,;.21,-.11,)| | ||
| Structure | 
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