| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein kinase CLK1 |
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| Ligand | BDBM50392636 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_854040 (CHEMBL2155337) |
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| IC50 | 2100±n/a nM |
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| Citation |  Loidreau, Y; Marchand, P; Dubouilh-Benard, C; Nourrisson, MR; Duflos, M; Lozach, O; Loaëc, N; Meijer, L; Besson, T Synthesis and biological evaluation of N-arylbenzo[b]thieno[3,2-d]pyrimidin-4-amines and their pyrido and pyrazino analogues as Ser/Thr kinase inhibitors. Eur J Med Chem58:171-83 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein kinase CLK1 |
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| Name: | Dual specificity protein kinase CLK1 |
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| Synonyms: | CDC-like kinase 1 | CDC-like kinase 1 (CLK1) | CDC2-like kinase 1 (CLK1) | CLK | CLK1 | CLK1_HUMAN | Dual specificity protein kinase CLK1 | Dual specificity protein kinase CLK1/CLK4 | Dual specificty protein kinase CLK1 |
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| Type: | Protein |
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| Mol. Mass.: | 57322.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P49759 |
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| Residue: | 484 |
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| Sequence: | MRHSKRTYCPDWDDKDWDYGKWRSSSSHKRRKRSHSSAQENKRCKYNHSKMCDSHYLESR
SINEKDYHSRRYIDEYRNDYTQGCEPGHRQRDHESRYQNHSSKSSGRSGRSSYKSKHRIH
HSTSHRRSHGKSHRRKRTRSVEDDEEGHLICQSGDVLSARYEIVDTLGEGAFGKVVECID
HKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIV
FELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSD
YTEAYNPKIKRDERTLINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPC
DVWSIGCILIEYYLGFTVFPTHDSKEHLAMMERILGPLPKHMIQKTRKRKYFHHDRLDWD
EHSSAGRYVSRRCKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRITLREALKHPFFDLL
KKSI
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| BDBM50392636 |
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| n/a |
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| Name | BDBM50392636 |
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| Synonyms: | CHEMBL2153529 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H8BrFN4S |
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| Mol. Mass. | 375.218 |
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| SMILES | Fc1cc(Br)ccc1Nc1ncnc2c3cccnc3sc12 |
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| Structure | 
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