Compile Data Set for Download or QSAR

Found 289 hits with Last Name = 'duflos' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aromatase (Homo sapiens (Human))	BDBM50179635 ((+)-5-[(4-chlorophenyl)(1H-imidazol-1-yl)methyl]-1...) Show SMILES Clc1ccc(cc1)C(c1ccc2[nH]ccc2c1)n1ccnc1 Show InChI InChI=1S/C18H14ClN3/c19-16-4-1-13(2-5-16)18(22-10-9-20-12-22)15-3-6-17-14(11-15)7-8-21-17/h1-12,18,21H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Nantes University Curated by ChEMBL					Assay Description Inhibition of CYP19				Bioorg Med Chem Lett 16: 1134-7 (2006) Article DOI: 10.1016/j.bmcl.2005.11.099 BindingDB Entry DOI: 10.7270/Q2B27TV6
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50179635 ((+)-5-[(4-chlorophenyl)(1H-imidazol-1-yl)methyl]-1...) Show SMILES Clc1ccc(cc1)C(c1ccc2[nH]ccc2c1)n1ccnc1 Show InChI InChI=1S/C18H14ClN3/c19-16-4-1-13(2-5-16)18(22-10-9-20-12-22)15-3-6-17-14(11-15)7-8-21-17/h1-12,18,21H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Nantes University Curated by ChEMBL					Assay Description Inhibition of CYP19				Bioorg Med Chem Lett 16: 1134-7 (2006) Article DOI: 10.1016/j.bmcl.2005.11.099 BindingDB Entry DOI: 10.7270/Q2B27TV6
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50179635 ((+)-5-[(4-chlorophenyl)(1H-imidazol-1-yl)methyl]-1...) Show SMILES Clc1ccc(cc1)C(c1ccc2[nH]ccc2c1)n1ccnc1 Show InChI InChI=1S/C18H14ClN3/c19-16-4-1-13(2-5-16)18(22-10-9-20-12-22)15-3-6-17-14(11-15)7-8-21-17/h1-12,18,21H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.3	n/a	n/a	n/a	n/a	n/a	n/a
Nantes University Curated by ChEMBL					Assay Description Inhibition of CYP19				Bioorg Med Chem Lett 16: 1134-7 (2006) Article DOI: 10.1016/j.bmcl.2005.11.099 BindingDB Entry DOI: 10.7270/Q2B27TV6
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50179639 (4-((1H-imidazol-1-yl)(1H-indol-5-yl)methyl)benzoni...) Show SMILES N#Cc1ccc(cc1)C(c1ccc2[nH]ccc2c1)n1ccnc1 Show InChI InChI=1S/C19H14N4/c20-12-14-1-3-15(4-2-14)19(23-10-9-21-13-23)17-5-6-18-16(11-17)7-8-22-18/h1-11,13,19,22H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19.3	n/a	n/a	n/a	n/a	n/a	n/a
Nantes University Curated by ChEMBL					Assay Description Inhibition of CYP19				Bioorg Med Chem Lett 16: 1134-7 (2006) Article DOI: 10.1016/j.bmcl.2005.11.099 BindingDB Entry DOI: 10.7270/Q2B27TV6
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50179637 (5-((4-chlorophenyl)(1H-imidazol-1-yl)methyl)-1-met...) Show SMILES Cn1ccc2cc(ccc12)C(c1ccc(Cl)cc1)n1ccnc1 Show InChI InChI=1S/C19H16ClN3/c1-22-10-8-15-12-16(4-7-18(15)22)19(23-11-9-21-13-23)14-2-5-17(20)6-3-14/h2-13,19H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23.7	n/a	n/a	n/a	n/a	n/a	n/a
Nantes University Curated by ChEMBL					Assay Description Inhibition of CYP19				Bioorg Med Chem Lett 16: 1134-7 (2006) Article DOI: 10.1016/j.bmcl.2005.11.099 BindingDB Entry DOI: 10.7270/Q2B27TV6
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM100152 (7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...) Show SMILES COc1ccc2c(c1)[nH]c1c(C)nccc21 Show InChI InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of human recombinant CLK1-GST expressed in Escherichia coli using GRSRSRSRSRSR as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50179636 (5-((4-fluorophenyl)(1H-imidazol-1-yl)methyl)-1H-in...) Show SMILES Fc1ccc(cc1)C(c1ccc2[nH]ccc2c1)n1ccnc1 Show InChI InChI=1S/C18H14FN3/c19-16-4-1-13(2-5-16)18(22-10-9-20-12-22)15-3-6-17-14(11-15)7-8-21-17/h1-12,18,21H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26.3	n/a	n/a	n/a	n/a	n/a	n/a
Nantes University Curated by ChEMBL					Assay Description Inhibition of CYP19				Bioorg Med Chem Lett 16: 1134-7 (2006) Article DOI: 10.1016/j.bmcl.2005.11.099 BindingDB Entry DOI: 10.7270/Q2B27TV6
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM100152 (7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...) Show SMILES COc1ccc2c(c1)[nH]c1c(C)nccc21 Show InChI InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Aromatase (Homo sapiens (Human))	BDBM50179638 (5-((3-chlorophenyl)(1H-imidazol-1-yl)methyl)-1H-in...) Show SMILES Clc1cccc(c1)C(c1ccc2[nH]ccc2c1)n1ccnc1 Show InChI InChI=1S/C18H14ClN3/c19-16-3-1-2-14(11-16)18(22-9-8-20-12-22)15-4-5-17-13(10-15)6-7-21-17/h1-12,18,21H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29.7	n/a	n/a	n/a	n/a	n/a	n/a
Nantes University Curated by ChEMBL					Assay Description Inhibition of CYP19				Bioorg Med Chem Lett 16: 1134-7 (2006) Article DOI: 10.1016/j.bmcl.2005.11.099 BindingDB Entry DOI: 10.7270/Q2B27TV6
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50075009 (1-Ethyl-5-[(4-fluoro-phenyl)-imidazol-1-yl-methyl]...) Show SMILES CCn1ccc2cc(ccc12)C(c1ccc(F)cc1)n1ccnc1 Show InChI InChI=1S/C20H18FN3/c1-2-23-11-9-16-13-17(5-8-19(16)23)20(24-12-10-22-14-24)15-3-6-18(21)7-4-15/h3-14,20H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Nantes University Curated by ChEMBL					Assay Description Inhibition of CYP19				Bioorg Med Chem Lett 16: 1134-7 (2006) Article DOI: 10.1016/j.bmcl.2005.11.099 BindingDB Entry DOI: 10.7270/Q2B27TV6
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM100152 (7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...) Show SMILES COc1ccc2c(c1)[nH]c1c(C)nccc21 Show InChI InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of DYRK1A (unknown origin)				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50424711 (CHEMBL2314163) Show SMILES COc1ccc2c(c1)oc1c(N)ncnc21 Show InChI InChI=1S/C11H9N3O2/c1-15-6-2-3-7-8(4-6)16-10-9(7)13-5-14-11(10)12/h2-5H,1H3,(H2,12,13,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of human recombinant CLK1-GST expressed in Escherichia coli using GRSRSRSRSRSR as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50424676 (CHEMBL2313912) Show SMILES COc1ccc2c(c1)sc1c(Nc3ccc4OCCOc4c3)ncnc21 Show InChI InChI=1S/C19H15N3O3S/c1-23-12-3-4-13-16(9-12)26-18-17(13)20-10-21-19(18)22-11-2-5-14-15(8-11)25-7-6-24-14/h2-5,8-10H,6-7H2,1H3,(H,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50424671 (CHEMBL2313917) Show SMILES COc1ccc2c(c1)sc1c(Nc3ccccc3Cl)ncnc21 Show InChI InChI=1S/C17H12ClN3OS/c1-22-10-6-7-11-14(8-10)23-16-15(11)19-9-20-17(16)21-13-5-3-2-4-12(13)18/h2-9H,1H3,(H,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50424660 (CHEMBL2313884) Show SMILES COc1ccc2c(c1)sc1c(Nc3ccc(cc3)N(C)C)ncnc21 Show InChI InChI=1S/C19H18N4OS/c1-23(2)13-6-4-12(5-7-13)22-19-18-17(20-11-21-19)15-9-8-14(24-3)10-16(15)25-18/h4-11H,1-3H3,(H,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM27439 (8-thia-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca...) Show SMILES Nc1ncnc2c3cccnc3sc12 Show InChI InChI=1S/C9H6N4S/c10-8-7-6(12-4-13-8)5-2-1-3-11-9(5)14-7/h1-4H,(H2,10,12,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma32P]ATP after 30 mins by scin...				Eur J Med Chem 58: 171-83 (2012) Article DOI: 10.1016/j.ejmech.2012.10.006 BindingDB Entry DOI: 10.7270/Q21G0NCJ
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50424676 (CHEMBL2313912) Show SMILES COc1ccc2c(c1)sc1c(Nc3ccc4OCCOc4c3)ncnc21 Show InChI InChI=1S/C19H15N3O3S/c1-23-12-3-4-13-16(9-12)26-18-17(13)20-10-21-19(18)22-11-2-5-14-15(8-11)25-7-6-24-14/h2-5,8-10H,6-7H2,1H3,(H,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of human recombinant CLK1-GST expressed in Escherichia coli using GRSRSRSRSRSR as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50424664 (CHEMBL2313924) Show SMILES COc1ccc2c(c1)sc1c(Nc3ccc(Br)cc3F)ncnc21 Show InChI InChI=1S/C17H11BrFN3OS/c1-23-10-3-4-11-14(7-10)24-16-15(11)20-8-21-17(16)22-13-5-2-9(18)6-12(13)19/h2-8H,1H3,(H,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50424663 (CHEMBL2313925) Show SMILES COc1ccc(Nc2ncnc3c4ccc(OC)cc4sc23)c(F)c1 Show InChI InChI=1S/C18H14FN3O2S/c1-23-10-4-6-14(13(19)7-10)22-18-17-16(20-9-21-18)12-5-3-11(24-2)8-15(12)25-17/h3-9H,1-2H3,(H,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50424660 (CHEMBL2313884) Show SMILES COc1ccc2c(c1)sc1c(Nc3ccc(cc3)N(C)C)ncnc21 Show InChI InChI=1S/C19H18N4OS/c1-23(2)13-6-4-12(5-7-13)22-19-18-17(20-11-21-19)15-9-8-14(24-3)10-16(15)25-18/h4-11H,1-3H3,(H,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of human recombinant CLK1-GST expressed in Escherichia coli using GRSRSRSRSRSR as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 3 (Homo sapiens (Human))	BDBM100152 (7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...) Show SMILES COc1ccc2c(c1)[nH]c1c(C)nccc21 Show InChI InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of DYRK3 (unknown origin)				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50424707 (CHEMBL2314167) Show SMILES COc1ccc(Nc2ncnc3c4ccc(OC)cc4oc23)cc1 Show InChI InChI=1S/C18H15N3O3/c1-22-12-5-3-11(4-6-12)21-18-17-16(19-10-20-18)14-8-7-13(23-2)9-15(14)24-17/h3-10H,1-2H3,(H,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50392636 (CHEMBL2153529) Show SMILES Fc1cc(Br)ccc1Nc1ncnc2c3cccnc3sc12 Show InChI InChI=1S/C15H8BrFN4S/c16-8-3-4-11(10(17)6-8)21-14-13-12(19-7-20-14)9-2-1-5-18-15(9)22-13/h1-7H,(H,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate and [gamma32P]ATP after 30 mins by sc...				Eur J Med Chem 58: 171-83 (2012) Article DOI: 10.1016/j.ejmech.2012.10.006 BindingDB Entry DOI: 10.7270/Q21G0NCJ
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (Homo sapiens (Human))	BDBM100152 (7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...) Show SMILES COc1ccc2c(c1)[nH]c1c(C)nccc21 Show InChI InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of DYRK2 (unknown origin)				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50424665 (CHEMBL2313923) Show SMILES COc1ccc2c(c1)sc1c(Nc3ccc(F)cc3F)ncnc21 Show InChI InChI=1S/C17H11F2N3OS/c1-23-10-3-4-11-14(7-10)24-16-15(11)20-8-21-17(16)22-13-5-2-9(18)6-12(13)19/h2-8H,1H3,(H,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50424680 (CHEMBL2313908) Show SMILES COc1ccc2c(c1)sc1c(Nc3ccc(OC)c(OC)c3)ncnc21 Show InChI InChI=1S/C19H17N3O3S/c1-23-12-5-6-13-16(9-12)26-18-17(13)20-10-21-19(18)22-11-4-7-14(24-2)15(8-11)25-3/h4-10H,1-3H3,(H,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50424711 (CHEMBL2314163) Show SMILES COc1ccc2c(c1)oc1c(N)ncnc21 Show InChI InChI=1S/C11H9N3O2/c1-15-6-2-3-7-8(4-6)16-10-9(7)13-5-14-11(10)12/h2-5H,1H3,(H2,12,13,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50424707 (CHEMBL2314167) Show SMILES COc1ccc(Nc2ncnc3c4ccc(OC)cc4oc23)cc1 Show InChI InChI=1S/C18H15N3O3/c1-22-12-5-3-11(4-6-12)21-18-17-16(19-10-20-18)14-8-7-13(23-2)9-15(14)24-17/h3-10H,1-2H3,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of human recombinant CLK1-GST expressed in Escherichia coli using GRSRSRSRSRSR as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50424668 (CHEMBL2313920) Show SMILES COc1ccc2c(c1)sc1c(Nc3ccc(Cl)cc3Cl)ncnc21 Show InChI InChI=1S/C17H11Cl2N3OS/c1-23-10-3-4-11-14(7-10)24-16-15(11)20-8-21-17(16)22-13-5-2-9(18)6-12(13)19/h2-8H,1H3,(H,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50424665 (CHEMBL2313923) Show SMILES COc1ccc2c(c1)sc1c(Nc3ccc(F)cc3F)ncnc21 Show InChI InChI=1S/C17H11F2N3OS/c1-23-10-3-4-11-14(7-10)24-16-15(11)20-8-21-17(16)22-13-5-2-9(18)6-12(13)19/h2-8H,1H3,(H,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of human recombinant CLK1-GST expressed in Escherichia coli using GRSRSRSRSRSR as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50424670 (CHEMBL2313918) Show SMILES COc1ccc2c(c1)sc1c(Nc3ccc(Cl)c(Cl)c3)ncnc21 Show InChI InChI=1S/C17H11Cl2N3OS/c1-23-10-3-4-11-14(7-10)24-16-15(11)20-8-21-17(16)22-9-2-5-12(18)13(19)6-9/h2-8H,1H3,(H,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50424703 (CHEMBL2313885) Show SMILES COc1ccc2c(c1)oc1c(Nc3ccc4OCOc4c3)ncnc21 Show InChI InChI=1S/C18H13N3O4/c1-22-11-3-4-12-14(7-11)25-17-16(12)19-8-20-18(17)21-10-2-5-13-15(6-10)24-9-23-13/h2-8H,9H2,1H3,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of human recombinant CLK1-GST expressed in Escherichia coli using GRSRSRSRSRSR as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50392636 (CHEMBL2153529) Show SMILES Fc1cc(Br)ccc1Nc1ncnc2c3cccnc3sc12 Show InChI InChI=1S/C15H8BrFN4S/c16-8-3-4-11(10(17)6-8)21-14-13-12(19-7-20-14)9-2-1-5-18-15(9)22-13/h1-7H,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma32P]ATP after 30 mins by scin...				Eur J Med Chem 58: 171-83 (2012) Article DOI: 10.1016/j.ejmech.2012.10.006 BindingDB Entry DOI: 10.7270/Q21G0NCJ
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50392634 (CHEMBL2153527) Show SMILES C1Oc2ccc(Nc3ncnc4c5cccnc5sc34)cc2O1 Show InChI InChI=1S/C16H10N4O2S/c1-2-10-13-14(23-16(10)17-5-1)15(19-7-18-13)20-9-3-4-11-12(6-9)22-8-21-11/h1-7H,8H2,(H,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma32P]ATP after 30 mins by scin...				Eur J Med Chem 58: 171-83 (2012) Article DOI: 10.1016/j.ejmech.2012.10.006 BindingDB Entry DOI: 10.7270/Q21G0NCJ
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50424664 (CHEMBL2313924) Show SMILES COc1ccc2c(c1)sc1c(Nc3ccc(Br)cc3F)ncnc21 Show InChI InChI=1S/C17H11BrFN3OS/c1-23-10-3-4-11-14(7-10)24-16-15(11)20-8-21-17(16)22-13-5-2-9(18)6-12(13)19/h2-8H,1H3,(H,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of human recombinant CLK1-GST expressed in Escherichia coli using GRSRSRSRSRSR as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50424662 (CHEMBL2313926) Show SMILES COc1ccc2c(c1)sc1c(Nc3ccc(cc3)C#N)ncnc21 Show InChI InChI=1S/C18H12N4OS/c1-23-13-6-7-14-15(8-13)24-17-16(14)20-10-21-18(17)22-12-4-2-11(9-19)3-5-12/h2-8,10H,1H3,(H,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50424703 (CHEMBL2313885) Show SMILES COc1ccc2c(c1)oc1c(Nc3ccc4OCOc4c3)ncnc21 Show InChI InChI=1S/C18H13N3O4/c1-22-11-3-4-12-14(7-11)25-17-16(12)19-8-20-18(17)21-10-2-5-13-15(6-10)24-9-23-13/h2-8H,9H2,1H3,(H,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM27439 (8-thia-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca...) Show SMILES Nc1ncnc2c3cccnc3sc12 Show InChI InChI=1S/C9H6N4S/c10-8-7-6(12-4-13-8)5-2-1-3-11-9(5)14-7/h1-4H,(H2,10,12,13)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate and [gamma32P]ATP after 30 mins by sc...				Eur J Med Chem 58: 171-83 (2012) Article DOI: 10.1016/j.ejmech.2012.10.006 BindingDB Entry DOI: 10.7270/Q21G0NCJ
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50424680 (CHEMBL2313908) Show SMILES COc1ccc2c(c1)sc1c(Nc3ccc(OC)c(OC)c3)ncnc21 Show InChI InChI=1S/C19H17N3O3S/c1-23-12-5-6-13-16(9-12)26-18-17(13)20-10-21-19(18)22-11-4-7-14(24-2)15(8-11)25-3/h4-10H,1-3H3,(H,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of human recombinant CLK1-GST expressed in Escherichia coli using GRSRSRSRSRSR as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50392631 (CHEMBL2153524) Show SMILES COc1ccc(Nc2ncnc3c4cccnc4sc23)cc1OC Show InChI InChI=1S/C17H14N4O2S/c1-22-12-6-5-10(8-13(12)23-2)21-16-15-14(19-9-20-16)11-4-3-7-18-17(11)24-15/h3-9H,1-2H3,(H,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate and [gamma32P]ATP after 30 mins by sc...				Eur J Med Chem 58: 171-83 (2012) Article DOI: 10.1016/j.ejmech.2012.10.006 BindingDB Entry DOI: 10.7270/Q21G0NCJ
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50424671 (CHEMBL2313917) Show SMILES COc1ccc2c(c1)sc1c(Nc3ccccc3Cl)ncnc21 Show InChI InChI=1S/C17H12ClN3OS/c1-22-10-6-7-11-14(8-10)23-16-15(11)19-9-20-17(16)21-13-5-3-2-4-12(13)18/h2-9H,1H3,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of human recombinant CLK1-GST expressed in Escherichia coli using GRSRSRSRSRSR as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50424694 (CHEMBL2313894) Show SMILES COc1ccc2c(c1)oc1c(Nc3ccc(Cl)cc3Cl)ncnc21 Show InChI InChI=1S/C17H11Cl2N3O2/c1-23-10-3-4-11-14(7-10)24-16-15(11)20-8-21-17(16)22-13-5-2-9(18)6-12(13)19/h2-8H,1H3,(H,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50424697 (CHEMBL2313891) Show SMILES COc1ccc2c(c1)oc1c(Nc3ccccc3Cl)ncnc21 Show InChI InChI=1S/C17H12ClN3O2/c1-22-10-6-7-11-14(8-10)23-16-15(11)19-9-20-17(16)21-13-5-3-2-4-12(13)18/h2-9H,1H3,(H,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50392630 (CHEMBL2153523) Show SMILES COc1ccc(Nc2ncnc3c4cccnc4sc23)cc1 Show InChI InChI=1S/C16H12N4OS/c1-21-11-6-4-10(5-7-11)20-15-14-13(18-9-19-15)12-3-2-8-17-16(12)22-14/h2-9H,1H3,(H,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma32P]ATP after 30 mins by scin...				Eur J Med Chem 58: 171-83 (2012) Article DOI: 10.1016/j.ejmech.2012.10.006 BindingDB Entry DOI: 10.7270/Q21G0NCJ
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50392631 (CHEMBL2153524) Show SMILES COc1ccc(Nc2ncnc3c4cccnc4sc23)cc1OC Show InChI InChI=1S/C17H14N4O2S/c1-22-12-6-5-10(8-13(12)23-2)21-16-15-14(19-9-20-16)11-4-3-7-18-17(11)24-15/h3-9H,1-2H3,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma32P]ATP after 30 mins by scin...				Eur J Med Chem 58: 171-83 (2012) Article DOI: 10.1016/j.ejmech.2012.10.006 BindingDB Entry DOI: 10.7270/Q21G0NCJ
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50392622 (CHEMBL2153515) Show SMILES COc1ccc(Nc2ncnc3c4ccccc4sc23)cc1OC Show InChI InChI=1S/C18H15N3O2S/c1-22-13-8-7-11(9-14(13)23-2)21-18-17-16(19-10-20-18)12-5-3-4-6-15(12)24-17/h3-10H,1-2H3,(H,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate and [gamma32P]ATP after 30 mins by sc...				Eur J Med Chem 58: 171-83 (2012) Article DOI: 10.1016/j.ejmech.2012.10.006 BindingDB Entry DOI: 10.7270/Q21G0NCJ
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50392603 (CHEMBL2153534) Show SMILES COc1ccc(Nc2ncnc3c2sc2cccnc32)cc1OC Show InChI InChI=1S/C17H14N4O2S/c1-22-11-6-5-10(8-12(11)23-2)21-17-16-15(19-9-20-17)14-13(24-16)4-3-7-18-14/h3-9H,1-2H3,(H,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate and [gamma32P]ATP after 30 mins by sc...				Eur J Med Chem 58: 171-83 (2012) Article DOI: 10.1016/j.ejmech.2012.10.006 BindingDB Entry DOI: 10.7270/Q21G0NCJ
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (RAT)	BDBM50424679 (CHEMBL2313909) Show SMILES COc1ccc2c(c1)sc1c(Nc3cc(OC)cc(OC)c3)ncnc21 Show InChI InChI=1S/C19H17N3O3S/c1-23-12-4-5-15-16(9-12)26-18-17(15)20-10-21-19(18)22-11-6-13(24-2)8-14(7-11)25-3/h4-10H,1-3H3,(H,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50424697 (CHEMBL2313891) Show SMILES COc1ccc2c(c1)oc1c(Nc3ccccc3Cl)ncnc21 Show InChI InChI=1S/C17H12ClN3O2/c1-22-10-6-7-11-14(8-10)23-16-15(11)19-9-20-17(16)21-13-5-3-2-4-12(13)18/h2-9H,1H3,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of human recombinant CLK1-GST expressed in Escherichia coli using GRSRSRSRSRSR as substrate				Eur J Med Chem 59: 283-95 (2013) Article DOI: 10.1016/j.ejmech.2012.11.030 BindingDB Entry DOI: 10.7270/Q2K075K7
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50392629 (CHEMBL2153522) Show SMILES N(c1ccccc1)c1ncnc2c3cccnc3sc12 Show InChI InChI=1S/C15H10N4S/c1-2-5-10(6-3-1)19-14-13-12(17-9-18-14)11-7-4-8-16-15(11)20-13/h1-9H,(H,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Rouen Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma32P]ATP after 30 mins by scin...				Eur J Med Chem 58: 171-83 (2012) Article DOI: 10.1016/j.ejmech.2012.10.006 BindingDB Entry DOI: 10.7270/Q21G0NCJ
					More data for this Ligand-Target Pair

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