| Reaction Details |
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 | Report a problem with these data |
| Target | D-amino-acid oxidase |
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| Ligand | BDBM50393049 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_853595 (CHEMBL2154050) |
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| IC50 | 2000±n/a nM |
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| Citation |  Berry, JF; Ferraris, DV; Duvall, B; Hin, N; Rais, R; Alt, J; Thomas, AG; Rojas, C; Hashimoto, K; Slusher, BS; Tsukamoto, T Synthesis and SAR of 1-hydroxy-1H-benzo[d]imidazol-2(3H)-ones as Inhibitors of D-Amino Acid Oxidase. ACS Med Chem Lett3:839-843 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D-amino-acid oxidase |
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| Name: | D-amino-acid oxidase |
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| Synonyms: | D-amino-acid oxidase (DAAO) | DAAO | DAMOX | DAO | OXDA_HUMAN |
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| Type: | Homodimer |
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| Mol. Mass.: | 39476.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14920 |
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| Residue: | 347 |
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| Sequence: | MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPN
NPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPR
ELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVN
CTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGG
IFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGP
SNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
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| BDBM50393049 |
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| n/a |
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| Name | BDBM50393049 |
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| Synonyms: | CHEMBL2152738 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H7FN2O2 |
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| Mol. Mass. | 182.1518 |
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| SMILES | Cc1cc2[nH]c(=O)n(O)c2cc1F |
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| Structure | 
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