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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Prostaglandin E2 receptor EP3 subtype | ||
| Ligand | BDBM50394649 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_857863 (CHEMBL2169496) | ||
| Ki | 678.4±n/a nM | ||
| Citation |  Tomasch, M; Schwed, JS; Kuczka, K; Meyer Dos Santos, S; Harder, S; Nüsing, RM; Paulke, A; Stark, H Fluorescent Human EP3 Receptor Antagonists. ACS Med Chem Lett3:774-779 (2012) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Prostaglandin E2 receptor EP3 subtype | |||
| Name: | Prostaglandin E2 receptor EP3 subtype | ||
| Synonyms: | PE2R3_HUMAN | PGE receptor, EP3 subtype | PGE2-R | PTGER3 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP3 subtype | Prostaglandin E2 receptor EP3 subtype (EP3) | Prostaglandin E2 receptor EP3A subtype (EP3A) | Prostaglandin E2 receptor EP3D subtype (EP3D) | Prostanoid EP3 receptor | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 43335.03 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P43115 | ||
| Residue: | 390 | ||
| Sequence: |
| ||
| BDBM50394649 | |||
| n/a | |||
| Name | BDBM50394649 | ||
| Synonyms: | CHEMBL2164613 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C42H34N2O9S | ||
| Mol. Mass. | 742.792 | ||
| SMILES | COc1cc(C\C=C\c2ccccc2C=CC(O)=O)ccc1OCCNC(=S)Nc1ccc(c(c1)C(O)=O)-c1c2ccc(O)cc2oc2cc(=O)ccc12 |w:14.14,(66.15,-44.12,;64.82,-43.36,;64.81,-41.82,;66.15,-41.04,;66.14,-39.5,;67.47,-38.73,;68.81,-39.5,;68.81,-41.04,;70.14,-41.81,;70.14,-43.35,;71.48,-44.12,;72.81,-43.35,;72.81,-41.81,;71.46,-41.04,;71.46,-39.5,;72.8,-38.73,;72.8,-37.19,;74.13,-36.42,;71.46,-36.42,;64.8,-38.74,;63.47,-39.51,;63.48,-41.05,;62.15,-41.82,;60.81,-41.06,;59.48,-41.83,;58.14,-41.06,;56.81,-41.83,;56.82,-43.37,;55.48,-41.07,;54.14,-41.84,;52.81,-41.07,;51.48,-41.84,;51.48,-43.38,;52.82,-44.15,;54.15,-43.38,;53.08,-45.67,;54.42,-46.43,;51.91,-46.66,;49.35,-44.62,;48.01,-43.85,;48.01,-42.31,;46.67,-41.55,;45.34,-42.32,;44.01,-41.55,;45.35,-43.86,;46.68,-44.63,;46.69,-46.17,;48.02,-46.94,;48.02,-48.48,;49.36,-49.24,;49.36,-50.78,;50.69,-48.47,;50.68,-46.93,;49.35,-46.16,)| | ||
| Structure | 
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