Reaction Details | |||
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Target | Prostaglandin E2 receptor EP3 subtype | ||
Ligand | BDBM50394650 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_857863 (CHEMBL2169496) | ||
Ki | 1264.6±n/a nM | ||
Citation | Tomasch, M; Schwed, JS; Kuczka, K; Meyer Dos Santos, S; Harder, S; Nüsing, RM; Paulke, A; Stark, H Fluorescent Human EP3 Receptor Antagonists. ACS Med Chem Lett3:774-779 (2012) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Prostaglandin E2 receptor EP3 subtype | |||
Name: | Prostaglandin E2 receptor EP3 subtype | ||
Synonyms: | PE2R3_HUMAN | PGE receptor, EP3 subtype | PGE2-R | PTGER3 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP3 subtype | Prostaglandin E2 receptor EP3 subtype (EP3) | Prostaglandin E2 receptor EP3A subtype (EP3A) | Prostaglandin E2 receptor EP3D subtype (EP3D) | Prostanoid EP3 receptor | ||
Type: | Enzyme | ||
Mol. Mass.: | 43335.03 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P43115 | ||
Residue: | 390 | ||
Sequence: |
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BDBM50394650 | |||
n/a | |||
Name | BDBM50394650 | ||
Synonyms: | CHEMBL2164614 | ||
Type | Small organic molecule | ||
Emp. Form. | C42H34N2O9S | ||
Mol. Mass. | 742.792 | ||
SMILES | COc1cc(C\C=C\c2ccccc2C=CC(O)=O)ccc1OCCNC(=S)Nc1ccc(C(O)=O)c(c1)-c1c2ccc(O)cc2oc2cc(=O)ccc12 |w:14.14,(31.57,-56.82,;30.24,-56.05,;30.24,-54.51,;31.57,-53.74,;31.57,-52.2,;32.91,-51.43,;34.24,-52.2,;35.58,-51.43,;36.91,-52.2,;36.91,-53.74,;38.24,-54.51,;39.58,-53.74,;39.58,-52.2,;38.24,-51.43,;38.24,-49.89,;39.58,-49.12,;39.58,-47.58,;40.91,-46.81,;38.24,-46.81,;30.24,-51.43,;28.91,-52.2,;28.91,-53.74,;27.57,-54.51,;26.24,-53.74,;24.91,-54.51,;23.58,-53.74,;22.25,-54.51,;22.25,-56.05,;20.9,-53.74,;19.58,-54.51,;19.58,-56.05,;18.24,-56.82,;16.91,-56.05,;15.58,-56.89,;15.58,-58.43,;14.25,-56.12,;16.91,-54.51,;18.24,-53.74,;14.78,-53.28,;14.78,-51.74,;16.11,-50.97,;16.11,-49.43,;14.78,-48.66,;14.78,-47.12,;13.44,-49.43,;13.44,-50.97,;12.11,-51.74,;12.11,-53.28,;10.77,-54.05,;10.77,-55.59,;9.44,-56.36,;12.11,-56.36,;13.44,-55.59,;13.44,-54.05,)| | ||
Structure |