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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Aldo-keto reductase family 1 member B1 | ||
| Ligand | BDBM50218200 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_857754 (CHEMBL2168781) | ||
| IC50 | 84000±n/a nM | ||
| Citation |  Takemura, M; Endo, S; Matsunaga, T; Soda, M; Zhao, HT; El-Kabbani, O; Tajima, K; Iinuma, M; Hara, A Selective inhibition of the tumor marker aldo-keto reductase family member 1B10 by oleanolic acid. J Nat Prod74:1201-6 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Aldo-keto reductase family 1 member B1 | |||
| Name: | Aldo-keto reductase family 1 member B1 | ||
| Synonyms: | AKR1B1 | ALDR1 | ALDR_HUMAN | ALR2 | AR | Aldo-keto reductase family 1 member B1 (AKR1B1) | Aldose Reductase (ALR2) | Aldose reductase | Aldose reductase (AR) | ||
| Type: | Protein | ||
| Mol. Mass.: | 35855.50 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P15121. 4LAU; 2IKI; 4LB4; 2FZD; 2FZ8; 1US0 | ||
| Residue: | 316 | ||
| Sequence: |
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| BDBM50218200 | |||
| n/a | |||
| Name | BDBM50218200 | ||
| Synonyms: | (3S,4aR,6aR,6bS,8aS,12aS,14aR,14bR)-8a-(hydroxymethyl)-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-ol | CHEMBL400074 | Erythrodiol | uvaol | ||
| Type | Small organic molecule | ||
| Emp. Form. | C30H50O2 | ||
| Mol. Mass. | 442.7168 | ||
| SMILES | CC1(C)CC[C@]2(CO)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1 |r,c:12| | ||
| Structure | 
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