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Targetchemokine (C-X-C motif) receptor 3
LigandBDBM50399981
Substrate/Competitorn/a
Meas. Tech.ChEMBL_877964
Ki 50.12±n/a nM
Citation Wijtmans MScholten DJRoumen LCanals MCusters HGlas MVreeker MCde Kanter FJde Graaf CSmit MJde Esch IJLeurs R Chemical subtleties in small-molecule modulation of peptide receptor function: the case of CXCR3 biaryl-type ligands. J Med Chem 55:10572-83 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
chemokine (C-X-C motif) receptor 3
Name:chemokine (C-X-C motif) receptor 3
Synonyms:AAO92295.1 | C-X-C chemokine receptor type 3 | C-X-C chemokine receptor type 3 (CXCR3) | C-X-C chemokine receptor type 3 (CXCR3A) | CXCR3A
Type:Enzyme Catalytic Domain
Mol. Mass.:40665.65
Organism:Homo sapiens (Human)
Description:n/a
Residue:368
Sequence:
MVLEVSDHQVLNDAEVAALLENFSSSYDYGENESDSCCTSPPCPQDFSLNFDRAFLPALY
SLLFLLGLLGNGAVAAVLLSRRTALSSTDTFLLHLAVADTLLVLTLPLWAVDAAVQWVFG
SGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPPARVTLTCLAVWGLCL
LFALPDFIFLSAHHDERLNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILA
VLLVSRGQRRLRAMRLVVVVVVAFALCWTPYHLVVLVDILMDLGALARNCGRESRVDVAK
SVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLLLRLGCPNQRGLQRQPSSSRRDSSWSET
SEASYSGL
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  Blast E-value cutoff:
BDBM50399981
n/a
NameBDBM50399981
Synonyms:CHEMBL2181450
TypeSmall organic molecule
Emp. Form.C25H31IN
Mol. Mass.472.4243
SMILESCC1(C)[C@H]2C[C@@H]1C(C[N+](C)(C)Cc1ccc(cc1)-c1ccccc1I)=CC2 |r,c:27|
Structure
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