| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 5 |
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| Ligand | BDBM50402737 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_886914 (CHEMBL2211870) |
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| EC50 | 62±n/a nM |
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| Citation |  Aguilar, N; Mir, M; Grima, PM; López, M; Segarra, V; Esteban, L; Moreno, I; Godessart, N; Tarrasón, G; Domenech, T; Vilella, D; Armengol, C; Córdoba, M; Sabaté, M; Casals, D; Domínguez, M Discovery of a novel class of zwitterionic, potent, selective and orally active S1P1 direct agonists. Bioorg Med Chem Lett22:7672-6 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 5 |
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| Name: | Sphingosine 1-phosphate receptor 5 |
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| Synonyms: | EDG8 | Endothelial differentiation sphingolipid G-protein-coupled receptor 8 | S1P5 | S1PR5 | S1PR5_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-8 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 41796.42 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 398 |
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| Sequence: | MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLV
LGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALT
ASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLD
ACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRA
RRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSL
LNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSF
SGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
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| BDBM50402737 |
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| n/a |
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| Name | BDBM50402737 |
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| Synonyms: | CHEMBL2207778 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H25FN4O3S |
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| Mol. Mass. | 468.544 |
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| SMILES | CCCCN(C(=O)c1ccccc1F)c1nnc(s1)-c1ccc(CN2CC(C2)C(O)=O)cc1 |
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| Structure | 
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