| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Proteinase-activated receptor 2 |
|---|
| Ligand | BDBM50412713 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_511265 (CHEMBL996091) |
|---|
| EC50 | 2511.89±n/a nM |
|---|
| Citation |  Seitzberg, JG; Knapp, AE; Lund, BW; Mandrup Bertozzi, S; Currier, EA; Ma, JN; Sherbukhin, V; Burstein, ES; Olsson, R Discovery of potent and selective small-molecule PAR-2 agonists. J Med Chem51:5490-3 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Proteinase-activated receptor 2 |
|---|
| Name: | Proteinase-activated receptor 2 |
|---|
| Synonyms: | F2RL1 | GPR11 | PAR2 | PAR2_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 44152.54 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1497756 |
|---|
| Residue: | 397 |
|---|
| Sequence: | MRSPSAAWLLGAAILLAASLSCSGTIQGTNRSSKGRSLIGKVDGTSHVTGKGVTVETVFS
VDEFSASVLTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALA
DLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNP
MGHSRKKANIAIGISLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMF
NYFLSLAIGVFLFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICF
TPSNLLLVVHYFLIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALL
CRSVRTVKQMQVSLTSKKHSRKSSSYSSSSTTVKTSY
|
|
|
|---|
| BDBM50412713 |
|---|
| n/a |
|---|
| Name | BDBM50412713 |
|---|
| Synonyms: | CHEMBL493704 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H16BrN3O2S |
|---|
| Mol. Mass. | 406.297 |
|---|
| SMILES | CC(=NNC(=O)[C@H]1[C@@H](CNC1=O)c1ccccc1)c1ccc(Br)s1 |r,w:2.2| |
|---|
| Structure | 
|
|---|
Search and Browse
